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NF2: NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

1 protein, 41 patents, 0 drugs, 0 trials, 3,523 NIH grants and 8,126 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNF2HGNC
NameNF2, moesin-ezrin-radixin like (MERLIN) tumor suppressorHGNC
NCBI Gene ID4771NCBI Gene
HGNC IDHGNC:7773HGNC
EnsemblENSG00000186575NCBI Gene
AliasesACN, BANF, SCH, SWNV, merlin, merlin-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35240Merlin5956Ensembl, GeneID, HGNCUniProt

Patents 41

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-196910P35240Espacenet
EP 4641201 A22025-10-296753P35240Espacenet
JP 2025517969 A2025-06-126753P35240Espacenet
JP 2025517970 A2025-06-126910P35240Espacenet
JP 2024123008 A2024-09-107306P35240Espacenet
JP 2024520815 A2024-05-247P35240Espacenet
JP 2024515629 A2024-04-1047P35240Espacenet
WO 2023022218 A2023-02-2326P35240Espacenet
US 11446398 B22022-09-2056396P35240Espacenet
JP 2022524081 A2022-04-27159367P35240Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3523

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1302,025NIH's project files
P30CA016672Cancer Center Support Grant932,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase462,025NIH's project files
P30CA006973Regional Oncology Research Center292,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award192,025NIH's project files
P50CA097257Brain Tumor SPORE Grant172,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)132,025NIH's project files
R01NS034783Function of NF2/Merlin in regulation of the Hippo/Salvador/Warts growth control pathway132,025NIH's project files
P30CA016058Cancer Center Support Grant122,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant122,025NIH's project files

Papers 8126

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826387PubTator, text miningPubMed
42825158PubTator, text miningPubMed
42816163PubTator, text miningPubMed
42811745PubTator, text miningPubMed
42780249PubTator, text miningPubMed
42770303PubTator, text miningPubMed
42764387PubTator, text miningPubMed
42751073PubTator, text miningPubMed
42739143PubTator, text miningPubMed
42732637PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license