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NFATC1: nuclear factor of activated T cells 1

1 protein, 30 patents, 0 drugs, 0 trials, 3,536 NIH grants and 5,979 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNFATC1HGNC
Namenuclear factor of activated T cells 1HGNC
NCBI Gene ID4772NCBI Gene
HGNC IDHGNC:7775HGNC
EnsemblENSG00000131196NCBI Gene
AliasesNF-ATC, NF-ATc1.2, NFAT2, NFATcNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O95644Nuclear factor of activated T-cells, cytoplasmic 19433Ensembl, GeneID, HGNCUniProt

Patents 30

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4640849 A22025-10-291994O95644Espacenet
EP 4641201 A22025-10-2913405O95644Espacenet
JP 2025147176 A2025-10-0615360O95644Espacenet
JP 2025519096 A2025-06-241994O95644Espacenet
JP 2025517969 A2025-06-1213405O95644Espacenet
JP 2025028160 A2025-02-2815360O95644Espacenet
KR 1020250010750 A2025-01-2115360O95644Espacenet
JP 2024123008 A2024-09-107393O95644Espacenet
JP 2024109657 A2024-08-1415199O95644Espacenet
JP 2023544161 A2023-10-2061O95644Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3536

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant212,025NIH's project files
P30CA008748Cancer Center Support Grant162,025NIH's project files
R01AI044938Inhibition of STAT3 and inflammatory cytokine production162,025NIH's project files
R01AR050401Cytokine Balance in Rheumatoid Arthritis152,025NIH's project files
R01AR046713Cytokine regulation of RA synoviocyte phenotype142,025NIH's project files
R01AI046712Activation of Macrophages in Human Autoimmune Diseases102,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant82,025NIH's project files
R01AI040127Signal transduction and gene induction in lymphocytes82,025NIH's project files
R01AR062173The IL-23/IL-17 Axis in Inflammatory Arthritis72,025NIH's project files
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses62,025NIH's project files

Papers 5979

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827110PubTator, text miningPubMed
42826626PubTator, text miningPubMed
42805952PubTator, text miningPubMed
42787358PubTator, text miningPubMed
42772373PubTator, text miningPubMed
42744168PubTator, text miningPubMed
42737778PubTator, text miningPubMed
42731286PubTator, text miningPubMed
42723851PubTator, text miningPubMed
42698993PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license