Gene · 4773
NFATC2: nuclear factor of activated T cells 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFATC2: nuclear factor of activated T cells 2. Genes, record 4773. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4773
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13469 | Nuclear factor of activated T-cells, cytoplasmic 2 | 925 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 11832 | Q13469 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15361 | Q13469 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11832 | Q13469 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32312 | Q13469 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15361 | Q13469 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15361 | Q13469 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32312 | Q13469 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 7402 | Q13469 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15200 | Q13469 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 32312 | Q13469 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,382
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFATC2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 25 | 2025 |
| R01AI040127 | Signal transduction and gene induction in lymphocytes | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 8 | 2025 |
| P50CA217694 | SPORE in Soft Tissue Sarcoma | 8 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 7 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 6 | 2025 |
| R35HL150778 | Ca2+ signaling Networks in Health and Disease | 6 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 5 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 2,382Source NIH's project files
See all 2,382 nih grantsPapers3,204
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| NFAM1 organizes a lipid raft-restricted DAPP1-PLCG2 module to drive M2-like GAM polarization via Ca²⁺-NFAT1 signaling in glioma. | Neuro Oncol | 2026 | 42820763 | PubTator, text mining | PubMed |
| Harmine Hydrochloride from Peganum harmala L. Targets NFAT1 for Proteasomal Degradation to Suppress Ovarian Cancer Progression. | Pharmaceuticals (Basel) | 2026 | 42797387 | PubTator, text mining | PubMed |
| Palmitic Acid Inhibits the Proliferation and Hypertrophy of Antler Chondrocytes by Disrupting Mitochondria-Associated Endoplasmic Reticulum Membrane Function. | Antioxidants (Basel) | 2026 | 42792147 | PubTator, text mining | PubMed |
| Avicularin and Senegenin Suppress TRPV3-Associated TSLP Expression in Human Keratinocytes. | Cells | 2026 | 42782759 | PubTator, text mining | PubMed |
| POLE2 of tumor cells promotes OPN secretion based on PCLAF to drive M2 macrophage polarization in clear cell renal cell carcinoma. | Cancer Gene Ther | 2026 | 42773249 | PubTator, text mining | PubMed |
| Intracellular Ca2+ balances the anti-inflammatory potential of IL-33-activated mast cells (MCs). | Cell Calcium | 2026 | 42753352 | PubTator, text mining | PubMed |
| Investigation of psychosocial stress and DNA methylation in genes related to immune response, metabolism, and calcium signaling among African American and White middle-aged adults. | Environ Epigenet | 2026 | 42698993 | PubTator, text mining | PubMed |
| Integrative Multi-Omics Analysis Reveals Convergent Epigenome and Transcriptome Changes in Parkinson's Disease. | Mov Disord | 2026 | 42610474 | PubTator, text mining | PubMed |
| Non-redundant functions of NFATc1 in survival and NFATc2 in generation of exhausted CD8+ T cells. | Front Immunol | 2026 | 42568576 | PubTator, text mining | PubMed |
| Transposable elements and homotypic niches drive immune dynamics and resistance in melanoma epigenetic-based immunotherapy. | Sci Adv | 2026 | 42566510 | PubTator, text mining | PubMed |
1 to 10 of 3,204
See all 3,204 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4773
GET https://conductscience.org/api/genes/v1/4773/patents?page=2