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Gene · 4774

NFIA: nuclear factor I A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFIA: nuclear factor I A. Genes, record 4774. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4774

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Gene

Symbol
NFIA
HGNC
Name
nuclear factor I A
HGNC
NCBI Gene ID
4774
NCBI Gene
HGNC ID
HGNC:7784
HGNC
Ensembl
ENSG00000162599
NCBI Gene
Aliases
BRMUTD, C1DELp32p31, CTF, DEL1P32P31, KIAA1439, NF-I/A, NF1-A, NFI-A, NFI-L
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q12857Nuclear factor 1 A-type5095Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4823630 A12026-10-217Q12857Espacenet
JP 2026004568 A2026-01-1455985Q12857Espacenet
EP 4650780 A22025-11-1911825Q12857Espacenet
WO 2025229918 A2025-11-064Q12857Espacenet
EP 4641201 A22025-10-2912593Q12857Espacenet
JP 2025147176 A2025-10-0615368Q12857Espacenet
JP 2025517969 A2025-06-1212593Q12857Espacenet
JP 2025517970 A2025-06-1211825Q12857Espacenet
JP 2025028160 A2025-02-2815368Q12857Espacenet
KR 1020250010750 A2025-01-2115368Q12857Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,444

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFIA papersNewest fiscal year
T32HL092332Training In Cell and Gene Therapy82025
P30DK063491Diabetes Research Center (DRC)62025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal62025
P30CA016672Cancer Center Support Grant52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
P30CA008748Cancer Center Support Grant42025
P30CA014195Cancer Center Support Grant (CCSG)32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA033572Cancer Center Support Grant32025
P50HD103555Baylor College of Medicine Intellectual and Developmental Disabilities Research Center32025

1 to 10 of 1,444Source NIH's project files

See all 1,444 nih grants

Papers1,435

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetics of Celiac Disease in Southern Brazil: High-Resolution HLA Haplotypes and Non-HLA Polymorphisms.HLA202642798292PubTator, text miningPubMed
Depletion of CARM1 slows in vivo tumorigenicity and rewires developmental programming in glioma stem-like cells.Cell Rep202642570242PubTator, text miningPubMed
Single-cell profiling uncovers extracellular vesicle-associated malignant plasma cell subpopulations driving multiple myeloma progression.Front Immunol202642529293PubTator, text miningPubMed
Delineation of a Novel Mirror Syndrome: NFIC Variants Cause Syndromic Intellectual Disability With Macrocephaly.Clin Genet202642498698PubTator, text miningPubMed
Glucocorticoid Signaling in PSC-Derived Neural Systems to Elucidate Mechanisms of Stress-Induced Psychiatric Vulnerability.Mol Neurobiol202642412256PubTator, text miningPubMed
Genome-wide rotational and translational phasing of nucleosomes with human transcription factors.Mol Cell202642392072PubTator, text miningPubMed
Molecular Characteristics and Differentiation Control Mechanisms of Bergmann Glia-Like Progenitors in the Postnatal Mouse Cerebellum.Glia202642358204PubTator, text miningPubMed
iAstrocytes model cytokine influences on complement expression and neuronal network synchronization.bioRxiv202642282708PubTator, text miningPubMed
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.Cell Rep202642201810PubTator, text miningPubMed
Transcription initiation profiling defines the regulatory logic of astrocyte gene regulation.bioRxiv202642146669PubTator, text miningPubMed

1 to 10 of 1,435

See all 1,435 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4774

GET https://conductscience.org/api/genes/v1/4774/patents?page=2