Gene · 4775
NFATC3: nuclear factor of activated T cells 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFATC3: nuclear factor of activated T cells 3. Genes, record 4775. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4775
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q12968 | Nuclear factor of activated T-cells, cytoplasmic 3 | 1,075 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 4015 | Q12968 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3597 | Q12968 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15362 | Q12968 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3597 | Q12968 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4015 | Q12968 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15362 | Q12968 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15362 | Q12968 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 7405 | Q12968 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15201 | Q12968 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 57975 | Q12968 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,291
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFATC3 papers | Newest fiscal year |
|---|---|---|---|
| P30MH092177 | Comprehensive NeuroHIV Center | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P50CA058223 | SPORE in Breast Cancer | 5 | 2025 |
| R35HL150778 | Ca2+ signaling Networks in Health and Disease | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| R01AI040127 | Signal transduction and gene induction in lymphocytes | 4 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,291Source NIH's project files
See all 1,291 nih grantsPapers1,451
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| ID3-directed sonogenetics to enhance osteogenesis and bone defect healing. | Int J Oral Sci | 2026 | 42733085 | PubTator, text mining | PubMed |
| Peripheral γδ T-cell remodeling in psoriasis is associated with effector-biased transcriptional organization and reduced representation of a circulating CSMD1-marked state. | Front Immunol | 2026 | 42694189 | PubTator, text mining | PubMed |
| Sweat gland tumors with NFATC3 gene fusions: a clinicopathological and molecular study of three cases. | Virchows Arch | 2026 | 42496690 | PubTator, text mining | PubMed |
| 3D-printed nanoengineered bioadhesive with tunable stiffness for uncovering electromechanotherapy-assisted cardiac microenvironment. | Biomaterials | 2026 | 41934819 | PubTator, text mining | PubMed |
| Hsa_circ_0000711 can serve as a novel biomarker for primary biliary cholangitis by promoting disease progression through the regulation of miR-185-5p and NFATc3. | RNA Biol | 2026 | 41879109 | PubTator, text mining | PubMed |
| FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression. | Cell Death Dis | 2026 | 41862445 | PubTator, text mining | PubMed |
| Lactylation, Crotonylation and Succinylation: Decoding Their Roles in the Progression of Cardiovascular Disease. | Rev Cardiovasc Med | 2026 | 41789347 | PubTator, text mining | PubMed |
| TrpC5 silencing reduces cell invasion and migration and enhances radiosensitivity in papillary thyroid carcinoma cells. | Front Cell Dev Biol | 2026 | 41768995 | PubTator, text mining | PubMed |
| Research Progress on the Biological Function, Disease-Driving Mechanism and Clinical Targeting Strategies of G3BP2. | Molecules | 2026 | 41752399 | PubTator, text mining | PubMed |
| The SLC41 Family of Magnesium Transporters: Molecular Regulators of Magnesium Homeostasis and Their Multifaceted Roles in Human Diseases. | Int J Mol Sci | 2026 | 41751808 | PubTator, text mining | PubMed |
1 to 10 of 1,451
See all 1,451 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4775
GET https://conductscience.org/api/genes/v1/4775/patents?page=2