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Gene · 4775

NFATC3: nuclear factor of activated T cells 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFATC3: nuclear factor of activated T cells 3. Genes, record 4775. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4775

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Gene

Symbol
NFATC3
HGNC
Name
nuclear factor of activated T cells 3
HGNC
NCBI Gene ID
4775
NCBI Gene
HGNC ID
HGNC:7777
HGNC
Ensembl
ENSG00000072736
NCBI Gene
Aliases
NF-AT4c, NFAT4, NFATX, n339260
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q12968Nuclear factor of activated T-cells, cytoplasmic 31,0752Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194015Q12968Espacenet
EP 4641201 A22025-10-293597Q12968Espacenet
JP 2025147176 A2025-10-0615362Q12968Espacenet
JP 2025517969 A2025-06-123597Q12968Espacenet
JP 2025517970 A2025-06-124015Q12968Espacenet
JP 2025028160 A2025-02-2815362Q12968Espacenet
KR 1020250010750 A2025-01-2115362Q12968Espacenet
JP 2024123008 A2024-09-107405Q12968Espacenet
JP 2024109657 A2024-08-1415201Q12968Espacenet
US 11446398 B22022-09-2057975Q12968Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,291

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFATC3 papersNewest fiscal year
P30MH092177Comprehensive NeuroHIV Center82025
P30CA016672Cancer Center Support Grant62025
P50CA058223SPORE in Breast Cancer52025
R35HL150778Ca2+ signaling Networks in Health and Disease52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA016056Roswell Park Cancer Center Support Grant42025
R01AI040127Signal transduction and gene induction in lymphocytes42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA008748Cancer Center Support Grant32025
P30CA016086Cancer Center Support Grant32025

1 to 10 of 1,291Source NIH's project files

See all 1,291 nih grants

Papers1,451

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ID3-directed sonogenetics to enhance osteogenesis and bone defect healing.Int J Oral Sci202642733085PubTator, text miningPubMed
Peripheral γδ T-cell remodeling in psoriasis is associated with effector-biased transcriptional organization and reduced representation of a circulating CSMD1-marked state.Front Immunol202642694189PubTator, text miningPubMed
Sweat gland tumors with NFATC3 gene fusions: a clinicopathological and molecular study of three cases.Virchows Arch202642496690PubTator, text miningPubMed
3D-printed nanoengineered bioadhesive with tunable stiffness for uncovering electromechanotherapy-assisted cardiac microenvironment.Biomaterials202641934819PubTator, text miningPubMed
Hsa_circ_0000711 can serve as a novel biomarker for primary biliary cholangitis by promoting disease progression through the regulation of miR-185-5p and NFATc3.RNA Biol202641879109PubTator, text miningPubMed
FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.Cell Death Dis202641862445PubTator, text miningPubMed
Lactylation, Crotonylation and Succinylation: Decoding Their Roles in the Progression of Cardiovascular Disease.Rev Cardiovasc Med202641789347PubTator, text miningPubMed
TrpC5 silencing reduces cell invasion and migration and enhances radiosensitivity in papillary thyroid carcinoma cells.Front Cell Dev Biol202641768995PubTator, text miningPubMed
Research Progress on the Biological Function, Disease-Driving Mechanism and Clinical Targeting Strategies of G3BP2.Molecules202641752399PubTator, text miningPubMed
The SLC41 Family of Magnesium Transporters: Molecular Regulators of Magnesium Homeostasis and Their Multifaceted Roles in Human Diseases.Int J Mol Sci202641751808PubTator, text miningPubMed

1 to 10 of 1,451

See all 1,451 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4775

GET https://conductscience.org/api/genes/v1/4775/patents?page=2