Gene · 4781
NFIB: nuclear factor I B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFIB: nuclear factor I B. Genes, record 4781. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4781
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00712 | Nuclear factor 1 B-type | 420 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705462 A2 | 2026-03-11 | 142 | O00712 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55992 | O00712 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10388 | O00712 | Espacenet |
| WO 2025229918 A | 2025-11-06 | 22 | O00712 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10712 | O00712 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15369 | O00712 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10712 | O00712 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10388 | O00712 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15369 | O00712 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15369 | O00712 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,621
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFIB papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 56 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 22 | 2025 |
| U24CA213274 | Coordinating center for the NCI small cell lung cancer research consortium | 7 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 6 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| R01DE023222 | Mutations and Target Genes in Adenoid Cystic Carcinoma | 6 | 2025 |
| R35CA231997 | Investigating molecular and cellular mechanisms of SCLC development to identify novel therapeutic strategies | 6 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 5 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA124435 | Stanford Cancer Institute | 4 | 2025 |
1 to 10 of 1,621Source NIH's project files
See all 1,621 nih grantsPapers2,223
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Atypical adenoid cystic carcinoma of the palate during pregnancy: a case report. | Front Oncol | 2026 | 42819075 | PubTator, text mining | PubMed |
| Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer. | Mol Oncol | 2026 | 42563417 | PubTator, text mining | PubMed |
| Integrated Transcriptomic Analysis of NOTCH1- and MYB-Associated Immune Features in SACC. | Int J Mol Sci | 2026 | 42511840 | PubTator, text mining | PubMed |
| Delineation of a Novel Mirror Syndrome: NFIC Variants Cause Syndromic Intellectual Disability With Macrocephaly. | Clin Genet | 2026 | 42498698 | PubTator, text mining | PubMed |
| Low-Grade Sweat Gland Carcinomas: A Review-A CME Article. | Am J Dermatopathol | 2026 | 42485130 | PubTator, text mining | PubMed |
| The role of mutant p53R175H in de novo activation of von Willebrand factor expression in tumor cells. | J Thromb Haemost | 2026 | 42448014 | PubTator, text mining | PubMed |
| Glucocorticoid Signaling in PSC-Derived Neural Systems to Elucidate Mechanisms of Stress-Induced Psychiatric Vulnerability. | Mol Neurobiol | 2026 | 42412256 | PubTator, text mining | PubMed |
| iAstrocytes model cytokine influences on complement expression and neuronal network synchronization. | bioRxiv | 2026 | 42282708 | PubTator, text mining | PubMed |
Non-coding Regulatory Variants in ASD (Autism Spectrum Disorders) Disrupt CTCF Domains and Shape Cell-Type-Specific Neurodevelopmental Landscapes Revealed by Single-Cell Analyses and Cortical Organoids. | Res Sq | 2026 | 42281968 | PubTator, text mining | PubMed |
| Pathogenic Mutations in the Tumor Microenvironment Drive Tumor Progression in Diffuse Large B-Cell Lymphoma Through Tumor-Stroma Cross-Talk. | Cancers (Basel) | 2026 | 42279281 | PubTator, text mining | PubMed |
1 to 10 of 2,223
See all 2,223 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4781
GET https://conductscience.org/api/genes/v1/4781/patents?page=2