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Gene · 4782

NFIC: nuclear factor I C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFIC: nuclear factor I C. Genes, record 4782. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4782

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Gene

Symbol
NFIC
HGNC
Name
nuclear factor I C
HGNC
NCBI Gene ID
4782
NCBI Gene
HGNC ID
HGNC:7786
HGNC
Ensembl
ENSG00000141905
NCBI Gene
Aliases
CTF, CTF5, NF-I, NF-I/C, NF1-C, NFI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08651Nuclear factor 1 C-type5082Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1912813P08651Espacenet
EP 4641201 A22025-10-2914276P08651Espacenet
JP 2025147176 A2025-10-0615370P08651Espacenet
JP 2025517969 A2025-06-1214276P08651Espacenet
JP 2025517970 A2025-06-1212813P08651Espacenet
JP 2025028160 A2025-02-2815370P08651Espacenet
KR 1020250010750 A2025-01-2115370P08651Espacenet
JP 2024109657 A2024-08-1415209P08651Espacenet
JP 2024518409 A2024-05-0142P08651Espacenet
KR 1020240005887 A2024-01-1241P08651Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,467

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFIC papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
R01EY013124Immunopathogenesis of Adenovirus Keratitis62025
P30CA016672Cancer Center Support Grant42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA068485Cancer Center Support Grant32025
P30DK019525University of Pennsylvania Diabetes Research Center32025
T32CA119925Integrated Biological Systems Training in Oncology32025
UL1TR002345Washington University Institute of Clinical and Translational Sciences32025

1 to 10 of 1,467Source NIH's project files

See all 1,467 nih grants

Papers1,961

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Temporal regulation of progenitor lineage progression and output by NFIs underlying human neocortical malformation.Neuron202642759511PubTator, text miningPubMed
Integration of Single-Cell Transcriptomics and Network-Based Machine Learning Identifies Bone Marrow Mesenchymal Stem Cell-Associated Candidate Biomarkers and Exploratory Immune Correlates in Osteoarthritis.
Curr Gene Ther202642634547PubTator, text miningPubMed
Delineation of a Novel Mirror Syndrome: NFIC Variants Cause Syndromic Intellectual Disability With Macrocephaly.Clin Genet202642498698PubTator, text miningPubMed
Single-nucleus multiomics unveils malignant cellular states, regulatory architectures and microenvironmental reorganization across the G-CIMP epigenomic transition in IDH-mutant glioma.bioRxiv202642327323PubTator, text miningPubMed
Genetic analysis of three familial cases of pure terminal 19p13.3 duplication caused by maternal balanced translocation t(19;21) (p13.3;p12).Front Genet202642306095PubTator, text miningPubMed
Retraction: NFIC suppressed the development of Glioma via modulating the balance of SHP2/PI3K and NF-κB/PTEN Signaling.PLoS One202642201871PubTator, text miningPubMed
Emerging roles of m6A modification in endodontic diseases: a systematic review.Epigenomics202642080597PubTator, text miningPubMed
Nuclear factor I-C as a novel candidate regulator in postoperative atrial fibrillation: integrated omics and proof-of-concept validation.Mol Cell Biochem202642048026PubTator, text miningPubMed
Genome-Wide DNA Methylation Patterns Predict Age in the Zebra Shark (Stegostoma tigrinum) and Provide Insight Into the Evolution of Vertebrate Aging.Mol Ecol202641930734PubTator, text miningPubMed
From reductionism to complex systems: Paradigm shift and knowledge evolution in competitive sports research using BERTopic.PLoS One202641911258PubTator, text miningPubMed

1 to 10 of 1,961

See all 1,961 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4782

GET https://conductscience.org/api/genes/v1/4782/patents