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Gene · 4783

NFIL3: nuclear factor, interleukin 3 regulated

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFIL3: nuclear factor, interleukin 3 regulated. Genes, record 4783. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4783

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Gene

Symbol
NFIL3
HGNC
Name
nuclear factor, interleukin 3 regulated
HGNC
NCBI Gene ID
4783
NCBI Gene
HGNC ID
HGNC:7787
HGNC
Ensembl
ENSG00000165030
NCBI Gene
Aliases
E4BP4, IL3BP1, NF-IL3A, NFIL3A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16649Nuclear factor interleukin-3-regulated protein4623Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456050Q16649Espacenet
JP 2026004568 A2026-01-1456051Q16649Espacenet
EP 4650780 A22025-11-193844Q16649Espacenet
EP 4641201 A22025-10-293406Q16649Espacenet
JP 2025147176 A2025-10-0615371Q16649Espacenet
JP 2025517969 A2025-06-123406Q16649Espacenet
JP 2025517970 A2025-06-123844Q16649Espacenet
JP 2025032204 A2025-03-1132344Q16649Espacenet
JP 2025028160 A2025-02-2815371Q16649Espacenet
KR 1020250010750 A2025-01-2115371Q16649Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,309

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFIL3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
R01AI100874The natural killer cell response against mouse cytomegalovirus infection72025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies52025
P30CA091842Cancer Center Support Grant52025
P30DK020572Michigan Diabetes Research Center (MDRC)52025
P30CA016058Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital42025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease42025

1 to 10 of 1,309Source NIH's project files

See all 1,309 nih grants

Papers1,539

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated phosphoproteome and transcriptome data-driven analysis of major transcription-regulatory phosphosites in NFIL3.Integr Biol (Camb)202642822860PubTator, text miningPubMed
E4BP4 interacts with PERK to form a feedback loop mediating cold-induced female reproductive disorders.Cell Stress Chaperones202642700913PubTator, text miningPubMed
Circadian proteolysis by the E3 ubiquitin ligase gp78 controls CYP3A4 activity in human hepatocytes.Biochem Pharmacol202642567488PubTator, text miningPubMed
Intervention with Polyvalent Bacterial Lysate Modulates T Helper Cell Subsets in Polish Children with Grass Pollen-Induced Allergic Rhinitis.Biomedicines202642512095PubTator, text miningPubMed
E4BP4 restrains effector-memory CD8+ T cell responses in systemic lupus erythematosus.Autoimmunity202642471227PubTator, text miningPubMed
D-Box Binding Protein (DBP) as a Circadian Output Regulator: Molecular Mechanisms, Tissue-Specific Functions, and Disease Relevance.Int J Mol Sci202642353162PubTator, text miningPubMed
E4BP4 safeguards brown fat mitochondria from obesity-induced fragmentation via ceramide repression.EMBO Rep202642332066PubTator, text miningPubMed
Clocking immunity: circadian modulation of NK cells and emerging timing perspectives.Front Immunol202642327792PubTator, text miningPubMed
Cellular Heterogeneity in Erectile Dysfunction: An In-silico Analysis Revealing PER1, BHLHE40, NFIL3, and KLF10 as Circadian Rhythm Genes.Curr Med Chem202642304925PubTator, text miningPubMed
Single-cell transcriptomic analysis deciphers heterogeneity and transcriptional regulatory programs of sepsis with different prognosis.Biol Direct202642215988PubTator, text miningPubMed

1 to 10 of 1,539

See all 1,539 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4783

GET https://conductscience.org/api/genes/v1/4783/patents?page=2