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Gene · 4793

NFKBIB: NFKB inhibitor beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFKBIB: NFKB inhibitor beta. Genes, record 4793. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4793

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Gene

Symbol
NFKBIB
HGNC
Name
NFKB inhibitor beta
HGNC
NCBI Gene ID
4793
NCBI Gene
HGNC ID
HGNC:7798
HGNC
Ensembl
ENSG00000104825
NCBI Gene
Aliases
IKBB, TRIP9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15653NF-kappa-B inhibitor beta3561Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-032Q15653Espacenet
JP 2026004568 A2026-01-1456009Q15653Espacenet
EP 4650780 A22025-11-194875Q15653Espacenet
EP 4641201 A22025-10-294446Q15653Espacenet
JP 2025147176 A2025-10-0615376Q15653Espacenet
JP 2025517969 A2025-06-124446Q15653Espacenet
JP 2025517970 A2025-06-124875Q15653Espacenet
JP 2025038035 A2025-03-184517Q15653Espacenet
JP 2025028160 A2025-02-2815376Q15653Espacenet
EP 4508096 A22025-02-1963Q15653Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,174

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFKBIB papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
K12HD000849Reproductive Scientist Development Program22025
P30AI117970District of Columbia Center for AIDS Research22025
P30CA008748Cancer Center Support Grant22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA016058Cancer Center Support Grant22025

1 to 10 of 1,174Source NIH's project files

See all 1,174 nih grants

Papers1,644

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
NFKBIB methylation by SETD3 controls NF-κB-mediated interferon activation during viral infection.FEBS J202642799327PubTator, text miningPubMed
The Flavivirus NS3 Protein: Its Multifaceted Roles and Therapeutic Potential.J Med Virol202641910366PubTator, text miningPubMed
NF-κB pathway gene expression is elevated in the midbrain of people with high-inflammation schizophrenia.Brain Behav Immun202641895666PubTator, text miningPubMed
Decoding the functional roles of circular RNAs linked to NF-κB pathway in carcinogenesis.Discov Oncol202540996665PubTator, text miningPubMed
Identification and 3D modeling of bioactive peptides from Lactobacillus brevis RAMULAB49 protein hydrolysate with in silico ERK1 phosphorylation inhibition activity targeting diabetic nephropathy.PLoS One202540982457PubTator, text miningPubMed
Regulatory roles of circular RNAs in Wnt and other oncogenic signaling pathways in breast cancer progression: a comprehensive review.Eur J Med Res202540804731PubTator, text miningPubMed
Identification of a stromal immunosuppressive barrier orchestrated by SPP1+/C1QC+ macrophages and CD8+ exhausted T cells driving gastric cancer immunotherapy resistance.Front Immunol202540740771PubTator, text miningPubMed
Multi-omics machine learning classifier and blood transcriptomic signature of Parkinson's disease.Res Sq202540585238PubTator, text miningPubMed
Aging and Altered Gravity: A Cellular Perspective.FASEB J202540577073PubTator, text miningPubMed
Downregulation of CPT2 promotes proliferation and migration through the TNFα/NF-κB pathway in cholangiocarcinoma.J Gastrointest Oncol202540386589PubTator, text miningPubMed

1 to 10 of 1,644

See all 1,644 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4793

GET https://conductscience.org/api/genes/v1/4793/patents?page=2