Gene · 4793
NFKBIB: NFKB inhibitor beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFKBIB: NFKB inhibitor beta. Genes, record 4793. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4793
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15653 | NF-kappa-B inhibitor beta | 356 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12539325 B2 | 2026-02-03 | 2 | Q15653 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56009 | Q15653 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4875 | Q15653 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4446 | Q15653 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15376 | Q15653 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4446 | Q15653 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4875 | Q15653 | Espacenet |
| JP 2025038035 A | 2025-03-18 | 4517 | Q15653 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15376 | Q15653 | Espacenet |
| EP 4508096 A2 | 2025-02-19 | 63 | Q15653 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,174
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFKBIB papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P50CA136393 | Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer | 6 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 3 | 2025 |
| K12HD000849 | Reproductive Scientist Development Program | 2 | 2025 |
| P30AI117970 | District of Columbia Center for AIDS Research | 2 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 2 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 1,174Source NIH's project files
See all 1,174 nih grantsPapers1,644
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| NFKBIB methylation by SETD3 controls NF-κB-mediated interferon activation during viral infection. | FEBS J | 2026 | 42799327 | PubTator, text mining | PubMed |
| The Flavivirus NS3 Protein: Its Multifaceted Roles and Therapeutic Potential. | J Med Virol | 2026 | 41910366 | PubTator, text mining | PubMed |
| NF-κB pathway gene expression is elevated in the midbrain of people with high-inflammation schizophrenia. | Brain Behav Immun | 2026 | 41895666 | PubTator, text mining | PubMed |
| Decoding the functional roles of circular RNAs linked to NF-κB pathway in carcinogenesis. | Discov Oncol | 2025 | 40996665 | PubTator, text mining | PubMed |
| Identification and 3D modeling of bioactive peptides from Lactobacillus brevis RAMULAB49 protein hydrolysate with in silico ERK1 phosphorylation inhibition activity targeting diabetic nephropathy. | PLoS One | 2025 | 40982457 | PubTator, text mining | PubMed |
| Regulatory roles of circular RNAs in Wnt and other oncogenic signaling pathways in breast cancer progression: a comprehensive review. | Eur J Med Res | 2025 | 40804731 | PubTator, text mining | PubMed |
| Identification of a stromal immunosuppressive barrier orchestrated by SPP1+/C1QC+ macrophages and CD8+ exhausted T cells driving gastric cancer immunotherapy resistance. | Front Immunol | 2025 | 40740771 | PubTator, text mining | PubMed |
| Multi-omics machine learning classifier and blood transcriptomic signature of Parkinson's disease. | Res Sq | 2025 | 40585238 | PubTator, text mining | PubMed |
| Aging and Altered Gravity: A Cellular Perspective. | FASEB J | 2025 | 40577073 | PubTator, text mining | PubMed |
| Downregulation of CPT2 promotes proliferation and migration through the TNFα/NF-κB pathway in cholangiocarcinoma. | J Gastrointest Oncol | 2025 | 40386589 | PubTator, text mining | PubMed |
1 to 10 of 1,644
See all 1,644 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4793
GET https://conductscience.org/api/genes/v1/4793/patents?page=2