Gene · 4800
NFYA: nuclear transcription factor Y subunit alpha
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFYA: nuclear transcription factor Y subunit alpha. Genes, record 4800. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4800
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P23511 | Nuclear transcription factor Y subunit alpha | 347 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56222 | P23511 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6999 | P23511 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6872 | P23511 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15384 | P23511 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6872 | P23511 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6999 | P23511 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15384 | P23511 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15384 | P23511 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15223 | P23511 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 629 | P23511 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,140
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFYA papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| ZIAAG000393 | Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 3 | 2025 |
| P30CA044579 | University of Virginia Cancer Center Support Grant | 3 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 3 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 3 | 2025 |
| T15LM007359 | Computation and Informatics in Biology and Medicine | 3 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 2 | 2025 |
1 to 10 of 1,140Source NIH's project files
See all 1,140 nih grantsPapers1,566
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| NFYA regulates the expression of CD44 via binding to upstream cis-element in breast cancer cells. | Biochimie | 2026 | 42749180 | PubTator, text mining | PubMed |
| Graph-Based Multi-Omics Integration Reveals Prognostic Histone Modification Reader Genes and Candidate Drug Targets in Colorectal Cancer. | Genes (Basel) | 2026 | 42650041 | PubTator, text mining | PubMed |
| Activation of EZH2 Promoter Is Mediated by MAPK Signaling Regulated Transcription Factors in Anaplastic Thyroid Cancer. | Int J Mol Sci | 2026 | 42511745 | PubTator, text mining | PubMed |
| HJURP upregulation, driven by transcription factor NFYA, promotes endometrial carcinoma progression via regulating RASSF8 ubiquitination. | Funct Integr Genomics | 2026 | 42321518 | PubTator, text mining | PubMed |
| Alternative Splicing of the NF-Y Subunit, NF-YA, in Neuroblastoma Phenotype Heterogeneity. | Cancers (Basel) | 2026 | 42279421 | PubTator, text mining | PubMed |
| NFYA Activates REG1A Expression to Promote Malignant Progression and Chemosensitivity in Rectal Cancer. | Ann Clin Lab Sci | 2026 | 42259544 | PubTator, text mining | PubMed |
| Single-nucleus and spatial transcriptomics analyses reveal interplay between evolutionary dynamics and energy metabolism in primary cardiac lymphoma. | Cancer Gene Ther | 2026 | 42174190 | PubTator, text mining | PubMed |
| NFYA-Mediated TTK Up-Regulation Drives Fast Cell Cycle Progression and Its Inhibition Leads to Mitotic Catastrophe in Triple Negative Breast Cancer. | Cancers (Basel) | 2026 | 42122120 | PubTator, text mining | PubMed |
| BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition. | Cell Mol Biol Lett | 2026 | 42069518 | PubTator, text mining | PubMed |
| Sporozoite egress from Plasmodium oocysts requires a trimeric NF-Y-like complex. | Commun Biol | 2026 | 42045549 | PubTator, text mining | PubMed |
1 to 10 of 1,566
See all 1,566 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4800
GET https://conductscience.org/api/genes/v1/4800/patents?page=2