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Gene · 4800

NFYA: nuclear transcription factor Y subunit alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NFYA: nuclear transcription factor Y subunit alpha. Genes, record 4800. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4800

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Gene

Symbol
NFYA
HGNC
Name
nuclear transcription factor Y subunit alpha
HGNC
NCBI Gene ID
4800
NCBI Gene
HGNC ID
HGNC:7804
HGNC
Ensembl
ENSG00000001167
NCBI Gene
Aliases
CBF-A, CBF-B, HAP2, NF-YA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23511Nuclear transcription factor Y subunit alpha3478Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456222P23511Espacenet
EP 4650780 A22025-11-196999P23511Espacenet
EP 4641201 A22025-10-296872P23511Espacenet
JP 2025147176 A2025-10-0615384P23511Espacenet
JP 2025517969 A2025-06-126872P23511Espacenet
JP 2025517970 A2025-06-126999P23511Espacenet
JP 2025028160 A2025-02-2815384P23511Espacenet
KR 1020250010750 A2025-01-2115384P23511Espacenet
JP 2024109657 A2024-08-1415223P23511Espacenet
US 11884978 B22024-01-30629P23511Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,140

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNFYA papersNewest fiscal year
P30CA016672Cancer Center Support Grant112025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging52025
P30CA068485Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
P30CA036727Buffett Cancer Center Support Grant32025
P30CA044579University of Virginia Cancer Center Support Grant32025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant32025
T15LM007359Computation and Informatics in Biology and Medicine32025
P01CA013106Targeting Transcription and Splicing in Cancer22025

1 to 10 of 1,140Source NIH's project files

See all 1,140 nih grants

Papers1,566

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
NFYA regulates the expression of CD44 via binding to upstream cis-element in breast cancer cells.Biochimie202642749180PubTator, text miningPubMed
Graph-Based Multi-Omics Integration Reveals Prognostic Histone Modification Reader Genes and Candidate Drug Targets in Colorectal Cancer.Genes (Basel)202642650041PubTator, text miningPubMed
Activation of EZH2 Promoter Is Mediated by MAPK Signaling Regulated Transcription Factors in Anaplastic Thyroid Cancer.Int J Mol Sci202642511745PubTator, text miningPubMed
HJURP upregulation, driven by transcription factor NFYA, promotes endometrial carcinoma progression via regulating RASSF8 ubiquitination.Funct Integr Genomics202642321518PubTator, text miningPubMed
Alternative Splicing of the NF-Y Subunit, NF-YA, in Neuroblastoma Phenotype Heterogeneity.Cancers (Basel)202642279421PubTator, text miningPubMed
NFYA Activates REG1A Expression to Promote Malignant Progression and Chemosensitivity in Rectal Cancer.Ann Clin Lab Sci202642259544PubTator, text miningPubMed
Single-nucleus and spatial transcriptomics analyses reveal interplay between evolutionary dynamics and energy metabolism in primary cardiac lymphoma.Cancer Gene Ther202642174190PubTator, text miningPubMed
NFYA-Mediated TTK Up-Regulation Drives Fast Cell Cycle Progression and Its Inhibition Leads to Mitotic Catastrophe in Triple Negative Breast Cancer.Cancers (Basel)202642122120PubTator, text miningPubMed
BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition.Cell Mol Biol Lett202642069518PubTator, text miningPubMed
Sporozoite egress from Plasmodium oocysts requires a trimeric NF-Y-like complex.Commun Biol202642045549PubTator, text miningPubMed

1 to 10 of 1,566

See all 1,566 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4800

GET https://conductscience.org/api/genes/v1/4800/patents?page=2