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NGF: nerve growth factor

1 protein, 151 patents, 5 drugs, 54 trials, 9,761 NIH grants and 25,373 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNGFHGNC
Namenerve growth factorHGNC
NCBI Gene ID4803NCBI Gene
HGNC IDHGNC:7808HGNC
EnsemblENSG00000134259NCBI Gene
AliasesBeta-NGF, HSAN5, NGFBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01138Beta-nerve growth factor24110Ensembl, GeneID, HGNCUniProt

Patents 151

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4762080 A12026-06-249P01138Espacenet
JP 2026518416 A2026-06-083P01138Espacenet
JP 2026515744 A2026-05-19363P01138Espacenet
EP 4705273 A22026-03-11254P01138Espacenet
EP 4705273 A22026-03-11465P01138Espacenet
EP 4650780 A22025-11-198634P01138Espacenet
JP 2025169942 A2025-11-141177P01138Espacenet
JP 2025147176 A2025-10-069355P01138Espacenet
JP 2025530891 A2025-09-18178P01138Espacenet
JP 2025529142 A2025-09-047137P01138Espacenet

Drugs 5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
FASINUMABCHEMBL2109528Beta-nerve growth factor inhibitorINHIBITORChEMBL
FULRANUMABCHEMBL1743023Beta-nerve growth factor inhibitorINHIBITORChEMBL
MEDI-578CHEMBL2109527Beta-nerve growth factor inhibitorINHIBITORChEMBL
PG-110CHEMBL2109526Beta-nerve growth factor inhibitorINHIBITORChEMBL
TANEZUMABCHEMBL2108567Beta-nerve growth factor inhibitorINHIBITORChEMBL

Trials 54

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04163419TANEZUMABPHASE2ClinicalTrials.gov
NCT03691974FASINUMABPHASE22023-03-01ClinicalTrials.gov
NCT03491904FASINUMABPHASE1ClinicalTrials.gov
NCT03304379FASINUMABPHASE32023-02-24ClinicalTrials.gov
NCT03285646FASINUMABPHASE32021-06-30ClinicalTrials.gov
NCT03161093FASINUMABPHASE32022-11-14ClinicalTrials.gov
NCT02725411TANEZUMABPHASE32020-08-11ClinicalTrials.gov
NCT02683239FASINUMABPHASE32023-10-13ClinicalTrials.gov
NCT02620020FASINUMABPHASE2/PHASE32019-08-01ClinicalTrials.gov
NCT02609828TANEZUMABPHASE32023-01-20ClinicalTrials.gov

NIH grants 9761

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant402,025NIH's project files
P30CA008748Cancer Center Support Grant342,025NIH's project files
R01AR060364Molecular Pathways of Pain Generation in Osteoarthritis202,025NIH's project files
R01AR064251Osteoarthritis Progression And Sensory Pathway Alterations202,025NIH's project files
P30EY014801Miami Center for Vision Research192,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)132,025NIH's project files
P30CA047904Cancer Center Support Grant112,025NIH's project files
P30CA016087Cancer Center Support Grant102,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)102,025NIH's project files

Papers 25373

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826726PubTator, text miningPubMed
42819332PubTator, text miningPubMed
42819214PubTator, text miningPubMed
42818942PubTator, text miningPubMed
42807803PubTator, text miningPubMed
42803635PubTator, text miningPubMed
42801791PubTator, text miningPubMed
42800594PubTator, text miningPubMed
42798274PubTator, text miningPubMed
42794833PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license