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Gene · 481

ATP1B1: ATPase Na+/K+ transporting subunit beta 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATP1B1: ATPase Na+/K+ transporting subunit beta 1. Genes, record 481. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/481

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Gene

Symbol
ATP1B1
HGNC
Name
ATPase Na+/K+ transporting subunit beta 1
HGNC
NCBI Gene ID
481
NCBI Gene
HGNC ID
HGNC:804
HGNC
Ensembl
ENSG00000143153
NCBI Gene
Aliases
ATP1B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P05026Sodium/potassium-transporting ATPase subunit beta-130311Ensembl, GeneID, HGNC

Source UniProt

Patents97

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438336P05026Espacenet
JP 2026004568 A2026-01-1438337P05026Espacenet
EP 4650780 A22025-11-198302P05026Espacenet
EP 4641202 A22025-10-29455P05026Espacenet
JP 2025529142 A2025-09-04501P05026Espacenet
US 12371689 B22025-07-29501P05026Espacenet
JP 2025517970 A2025-06-128302P05026Espacenet
JP 2025062604 A2025-04-147551P05026Espacenet
JP 2025062604 A2025-04-147552P05026Espacenet
JP 2025032204 A2025-03-1124955P05026Espacenet

1 to 10 of 97

See all 97 patents

Drugs6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACETYLDIGITOXINCHEMBL3545057Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DESLANOSIDECHEMBL1614Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DIGITOXINCHEMBL254219Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DIGOXINCHEMBL1751Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
ISTAROXIMECHEMBL2093999Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
LANATOSIDE CCHEMBL506569Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL

Trials55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,651

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATP1B1 papersNewest fiscal year
P30DK063491Diabetes Research Center (DRC)92025
P30CA016672Cancer Center Support Grant52025
P30CA008748Cancer Center Support Grant42025
P30CA015704Cancer Center Support Grant42025
P20GM103446Delaware INBRE32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30CA068485Cancer Center Support Grant32025
P30ES005605Environmental Health Sciences Research Center32025
P30EY014801Miami Center for Vision Research32025
T32EY014537Research Training Program in Vision Science32025

1 to 10 of 1,651Source NIH's project files

See all 1,651 nih grants

Papers3,412

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Establishment of an Indirect ELISA Detection Method for Porcine Reproductive and Respiratory Syndrome Virus NSP10.Vet Sci202642655813PubTator, text miningPubMed
An Endemic Region of Thiamine-Responsive Megaloblastic Anemia Caused by an SLC19A2 c.1223+1G>A Founder Mutation.Int J Mol Sci202642511616PubTator, text miningPubMed
Early-onset non-oliguric hyperkalaemia in a moderate preterm infant following maternal magnesium sulfate therapy.BMJ Case Rep202642498323PubTator, text miningPubMed
The Deubiquitinating Enzyme USP9X Regulates the Protein Stability of the FAM49B in Clear Cell Renal Cell Carcinoma.J Proteome Res202642463156PubTator, text miningPubMed
Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir.Sci Adv202642319933PubTator, text miningPubMed
Mechanisms of disassembly at the actin filament pointed and barbed ends.Sci Adv202641931606PubTator, text miningPubMed
X-linked Emery-Dreifuss muscular dystrophy caused by a novel FHL1 mutation: A case report.J Int Med Res202641839840PubTator, text miningPubMed
Glycohypoxia: a hypothesis linking chronic hyperglycemia to functional hypoxia and diabetic complications in type 2 diabetes.Med Gas Res202641830794PubTator, text miningPubMed
Wogonin derivative V8 enhances bortezomib efficacy in gastric carcinoma by disrupting lysosome-mediated drug resistance.World J Gastroenterol202641809875PubTator, text miningPubMed
Analysis of clinical and genomic features in a Chinese cohort with NRG1 variations: a retrospective study.Transl Lung Cancer Res202641808714PubTator, text miningPubMed

1 to 10 of 3,412

See all 3,412 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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