Gene · 481
ATP1B1: ATPase Na+/K+ transporting subunit beta 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATP1B1: ATPase Na+/K+ transporting subunit beta 1. Genes, record 481. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/481
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | 303 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents97
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38336 | P05026 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38337 | P05026 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8302 | P05026 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 455 | P05026 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 501 | P05026 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 501 | P05026 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8302 | P05026 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7551 | P05026 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7552 | P05026 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24955 | P05026 | Espacenet |
1 to 10 of 97
See all 97 patentsDrugs6
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ACETYLDIGITOXIN | CHEMBL3545057 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DESLANOSIDE | CHEMBL1614 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DIGITOXIN | CHEMBL254219 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DIGOXIN | CHEMBL1751 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| ISTAROXIME | CHEMBL2093999 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| LANATOSIDE C | CHEMBL506569 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
Trials55
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07272902 | DIGOXIN | ClinicalTrials.gov | ||
| NCT07047209 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT07025850 | DIGOXIN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT06701812 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06657404 | DIGOXIN | ClinicalTrials.gov | ||
| NCT06588699 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06322017 | DIGOXIN | ClinicalTrials.gov | ||
| NCT06240403 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06030622 | DIGOXIN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT05975021 | ISTAROXIME | PHASE1/PHASE2 | ClinicalTrials.gov |
1 to 10 of 55
See all 55 trialsNIH grants1,651
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATP1B1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK063491 | Diabetes Research Center (DRC) | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| P20GM103446 | Delaware INBRE | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 3 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 3 | 2025 |
| T32EY014537 | Research Training Program in Vision Science | 3 | 2025 |
1 to 10 of 1,651Source NIH's project files
See all 1,651 nih grantsPapers3,412
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Establishment of an Indirect ELISA Detection Method for Porcine Reproductive and Respiratory Syndrome Virus NSP10. | Vet Sci | 2026 | 42655813 | PubTator, text mining | PubMed |
| An Endemic Region of Thiamine-Responsive Megaloblastic Anemia Caused by an SLC19A2 c.1223+1G>A Founder Mutation. | Int J Mol Sci | 2026 | 42511616 | PubTator, text mining | PubMed |
| Early-onset non-oliguric hyperkalaemia in a moderate preterm infant following maternal magnesium sulfate therapy. | BMJ Case Rep | 2026 | 42498323 | PubTator, text mining | PubMed |
| The Deubiquitinating Enzyme USP9X Regulates the Protein Stability of the FAM49B in Clear Cell Renal Cell Carcinoma. | J Proteome Res | 2026 | 42463156 | PubTator, text mining | PubMed |
| Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir. | Sci Adv | 2026 | 42319933 | PubTator, text mining | PubMed |
| Mechanisms of disassembly at the actin filament pointed and barbed ends. | Sci Adv | 2026 | 41931606 | PubTator, text mining | PubMed |
| X-linked Emery-Dreifuss muscular dystrophy caused by a novel FHL1 mutation: A case report. | J Int Med Res | 2026 | 41839840 | PubTator, text mining | PubMed |
| Glycohypoxia: a hypothesis linking chronic hyperglycemia to functional hypoxia and diabetic complications in type 2 diabetes. | Med Gas Res | 2026 | 41830794 | PubTator, text mining | PubMed |
| Wogonin derivative V8 enhances bortezomib efficacy in gastric carcinoma by disrupting lysosome-mediated drug resistance. | World J Gastroenterol | 2026 | 41809875 | PubTator, text mining | PubMed |
| Analysis of clinical and genomic features in a Chinese cohort with NRG1 variations: a retrospective study. | Transl Lung Cancer Res | 2026 | 41808714 | PubTator, text mining | PubMed |
1 to 10 of 3,412
See all 3,412 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/481
GET https://conductscience.org/api/genes/v1/481/patents?page=2