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Gene · 4818

NKG7: natural killer cell granule protein 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NKG7: natural killer cell granule protein 7. Genes, record 4818. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4818

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Gene

Symbol
NKG7
HGNC
Name
natural killer cell granule protein 7
HGNC
NCBI Gene ID
4818
NCBI Gene
HGNC ID
HGNC:7830
HGNC
Ensembl
ENSG00000105374
NCBI Gene
Aliases
GIG1, GMP-17, p15-TIA-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16617Protein NKG71650Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-069375Q16617Espacenet
JP 2025529142 A2025-09-042847Q16617Espacenet
JP 2025529142 A2025-09-047143Q16617Espacenet
US 12371689 B22025-07-292847Q16617Espacenet
US 12371689 B22025-07-297143Q16617Espacenet
JP 2025028160 A2025-02-289375Q16617Espacenet
KR 1020250010750 A2025-01-219375Q16617Espacenet
JP 2024109657 A2024-08-149382Q16617Espacenet
US 11446398 B22022-09-2055498Q16617Espacenet
US 11400116 B22022-08-023321Q16617Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,401

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNKG7 papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award182025
P30CA008748Cancer Center Support Grant112025
P30CA016672Cancer Center Support Grant102025
P50CA121974Yale SPORE in Skin Cancer72025
P01AI039671Costimulatory Mechanisms of Autoimmunity62025
P30CA006973Regional Oncology Research Center62025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital62025
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)62025
P51OD011132Emory National Primate Research Center62025
P30CA016520Abramson Cancer Center Support Grant52025

1 to 10 of 1,401Source NIH's project files

See all 1,401 nih grants

Papers1,677

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Longxue tongluo capsule enhances ischemic stroke recovery via microbiota-metabolite-gene interactions.Metab Brain Dis202642804018PubTator, text miningPubMed
Single-cell RNA sequencing reveals compartment-specific immune and tumor cell states in a contiguous spinal metastasis.Neurooncol Adv202642757049PubTator, text miningPubMed
Single-cell RNA sequencing reveals distinct immune interaction networks in primary and reactivated HHV-6B infection.J Infect Dis202642682208PubTator, text miningPubMed
Distinct T Cell Repertoires in Spinal Entheses and Synovial Fluids in Ankylosing Spondylitis.Phenomics202642614581PubTator, text miningPubMed
Cytotoxic CD4+ T Cells in Visceral Leishmaniasis Patients.Parasite Immunol202642609202PubTator, text miningPubMed
Natural Killer Cell Granule Protein (NKG7) promotes the development of vaccine-induced anti-fungal Th1 cells.PLoS Pathog202642536677PubTator, text miningPubMed
[A multi-level study of androgen deprivation therapy on the immune microenvironment in prostate cancer].Beijing Da Xue Xue Bao Yi Xue Ban202642493444PubTator, text miningPubMed
Proliferation- and cytotoxic immune signatures identify chemotherapy-responsive bladder tumors in a molecular subtype dependent manner.NPJ Precis Oncol202642399473PubTator, text miningPubMed
Acute exercise shifts inferred immune cell composition and cytotoxic gene programs in pediatric sickle cell anemia.3 Biotech202642375599PubTator, text miningPubMed
Human NKT10 cells are enriched in cord-derived invariant natural killer T cells and mediate immune-regulation in a xenogeneic graft-versus-host disease model.Front Immunol202642358969PubTator, text miningPubMed

1 to 10 of 1,677

See all 1,677 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4818

GET https://conductscience.org/api/genes/v1/4818/patents?page=2