Gene · 482
ATP1B2: ATPase Na+/K+ transporting subunit beta 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATP1B2: ATPase Na+/K+ transporting subunit beta 2. Genes, record 482. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/482
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14415 | Sodium/potassium-transporting ATPase subunit beta-2 | 290 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12636345 B2 | 2026-05-26 | 48 | P14415 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38339 | P14415 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 502 | P14415 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 502 | P14415 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7554 | P14415 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24958 | P14415 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 24958 | P14415 | Espacenet |
| US 12090170 B2 | 2024-09-17 | 48 | P14415 | Espacenet |
| JP 2023523730 A | 2023-06-07 | 2 | P14415 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 24958 | P14415 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs6
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ACETYLDIGITOXIN | CHEMBL3545057 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DESLANOSIDE | CHEMBL1614 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DIGITOXIN | CHEMBL254219 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| DIGOXIN | CHEMBL1751 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| ISTAROXIME | CHEMBL2093999 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
| LANATOSIDE C | CHEMBL506569 | Sodium/potassium-transporting ATPase inhibitor | INHIBITOR | ChEMBL |
Trials55
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07272902 | DIGOXIN | ClinicalTrials.gov | ||
| NCT07047209 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT07025850 | DIGOXIN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT06701812 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06657404 | DIGOXIN | ClinicalTrials.gov | ||
| NCT06588699 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06322017 | DIGOXIN | ClinicalTrials.gov | ||
| NCT06240403 | DIGOXIN | PHASE2 | ClinicalTrials.gov | |
| NCT06030622 | DIGOXIN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT05975021 | ISTAROXIME | PHASE1/PHASE2 | ClinicalTrials.gov |
1 to 10 of 55
See all 55 trialsNIH grants428
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATP1B2 papers | Newest fiscal year |
|---|---|---|---|
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| P20GM103446 | Delaware INBRE | 2 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 2 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 2 | 2025 |
| R01AI104870 | Discriminating the contributions of CCR4 and CCR7 to thymic central tolerance | 2 | 2025 |
| T32MH020016 | Neuroscience Research Training | 2 | 2025 |
| U19AI057229 | Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro | 2 | 2025 |
| U19AI077439 | Immune-driven Airway Epithelial Dysfunction in Muco-obstructive Asthma | 2 | 2025 |
| U19AI089992 | Immune signatures of vaccine responses in vulnerable populations | 2 | 2025 |
| U19AI125357 | Innate Immunity and Viral Infection in Asthma | 2 | 2025 |
1 to 10 of 428Source NIH's project files
See all 428 nih grantsPapers349
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| RNF185 destabilizes specific membrane proteins that span all ERAD branches. | bioRxiv | 2026 | 42818288 | PubTator, text mining | PubMed |
| ACSA2 is not astrocyte-specific: implications for cell sorting strategies in the rodent brain. | Front Cell Neurosci | 2026 | 41788196 | PubTator, text mining | PubMed |
| Monitoring glioblastoma extracellular vesicle evolution using a nanodiagnostic platform to detect glioma stem cells driving recurrent disease. | Sci Adv | 2026 | 41616062 | PubTator, text mining | PubMed |
| Developmental Expression of Membrane Pumps and Ion Channels in Human Vestibular Endolymph Homeostasis. | Dev Neurobiol | 2026 | 41581228 | PubTator, text mining | PubMed |
| A bioinformatics analysis to identify shared molecular pathways and hub genes between NAFLD and Gestational Diabetes Mellitus. | Gastroenterol Hepatol Bed Bench | 2025 | 42137128 | PubTator, text mining | PubMed |
| Identification the Tumor Mechanics-Related Biomarkers in Gastric Cancer Patients Based on Bioinformatics and Machine Learning. | Int J Gen Med | 2025 | 41438119 | PubTator, text mining | PubMed |
| The genetic architecture of brainstem structures. | Nat Commun | 2025 | 41372214 | PubTator, text mining | PubMed |
| Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality. | JCI Insight | 2025 | 41212055 | PubTator, text mining | PubMed |
| Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury. | Front Immunol | 2025 | 41142807 | PubTator, text mining | PubMed |
| The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra. | Nat Commun | 2025 | 40759663 | PubTator, text mining | PubMed |
1 to 10 of 349
See all 349 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/482
GET https://conductscience.org/api/genes/v1/482/patents?page=2