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Gene · 4824

NKX3-1: NK3 homeobox 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NKX3-1: NK3 homeobox 1. Genes, record 4824. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4824

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Gene

Symbol
NKX3-1
HGNC
Name
NK3 homeobox 1
HGNC
NCBI Gene ID
4824
NCBI Gene
HGNC ID
HGNC:7838
HGNC
Ensembl
ENSG00000167034
NCBI Gene
Aliases
BAPX2, NKX3, NKX3.1, NKX3A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99801Homeobox protein Nkx-3.12341Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-2910696Q99801Espacenet
JP 2025147176 A2025-10-0615399Q99801Espacenet
JP 2025517969 A2025-06-1210696Q99801Espacenet
JP 2025028160 A2025-02-2815399Q99801Espacenet
KR 1020250010750 A2025-01-2115399Q99801Espacenet
EP 4487869 A22025-01-08222Q99801Espacenet
JP 2024123008 A2024-09-107356Q99801Espacenet
JP 2024109657 A2024-08-1415238Q99801Espacenet
KR 1020240027895 A2024-03-04414Q99801Espacenet
JP 2023036863 A2023-03-14414Q99801Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,220

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNKX3-1 papersNewest fiscal year
P50CA097186The Pacific Northwest Prostate Cancer SPORE562025
P30CA008748Cancer Center Support Grant422025
P30CA006973Regional Oncology Research Center382025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer362025
P30CA016672Cancer Center Support Grant262025
P50CA186786Michigan Prostate SPORE 2025-2030192025
P30CA015704Cancer Center Support Grant182025
P50CA092629SPORE in Prostate Cancer182025
P30CA013696Cancer Center Support Grant162025
P30CA016056Roswell Park Cancer Center Support Grant162025

1 to 10 of 2,220Source NIH's project files

See all 2,220 nih grants

Papers3,429

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Primary Neoplasms of the Seminal Vesicles: A Narrative Review of Carcinoma and the Rarer Non-Epithelial and Biphasic Tumours.Diagnostics (Basel)202642793728PubTator, text miningPubMed
NK3 subsets are linked to NK cell exhaustion and immunotherapy responsiveness in tumor.Semin Oncol202642762807PubTator, text miningPubMed
Urothelial carcinoma of the bladder with prostatic stromal invasion and early postoperative bone metastases: a case report.Front Urol202642698475PubTator, text miningPubMed
Occult Esophageal Squamous Cell Carcinoma Presenting as Bone-Predominant Carcinoma of Unknown Primary: A Case Report of a p40-Negative Vertebral Metastasis.Diagnostics (Basel)202642651078PubTator, text miningPubMed
Reappraisal of Endobronchial Polypoid Adenocarcinoma of the Lung: A Clinicopathological Analysis of 11 Cases.Am J Surg Pathol202642638334PubTator, text miningPubMed
Post-translational modifications in prostate cancer: coordinated oncogenic networks and clinical implications.Biochim Biophys Acta Rev Cancer202642637058PubTator, text miningPubMed
Occult Metastatic Prostate Carcinoma Presenting With Decompensated Heart Failure and Bicytopenia.Cureus202642597963PubTator, text miningPubMed
Prostate Cancer Recurrence Mimicking a Primary Paranasal Sinus Tumor on 18F-FDG PET/CT During Treatment for Metastases After 10 Years of Remission.Case Rep Radiol202642569055PubTator, text miningPubMed
Enzalutamide promotes an early plasticity-associated transcriptional state without terminal neuroendocrine differentiation in prostate cancer cells.Front Oncol202642568401PubTator, text miningPubMed
Prostate Cancer Associated with Muir-Torre Syndrome: A Rare Case Report and Literature Review.Case Rep Oncol202642541269PubTator, text miningPubMed

1 to 10 of 3,429

See all 3,429 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4824

GET https://conductscience.org/api/genes/v1/4824/patents?page=2