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Gene · 483

ATP1B3: ATPase Na+/K+ transporting subunit beta 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATP1B3: ATPase Na+/K+ transporting subunit beta 3. Genes, record 483. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/483

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Gene

Symbol
ATP1B3
HGNC
Name
ATPase Na+/K+ transporting subunit beta 3
HGNC
NCBI Gene ID
483
NCBI Gene
HGNC ID
HGNC:806
HGNC
Ensembl
ENSG00000069849
NCBI Gene
Aliases
ATPB-3, CD298, FLJ29027
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P54709Sodium/potassium-transporting ATPase subunit beta-32798Ensembl, GeneID, HGNC

Source UniProt

Patents105

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438340P54709Espacenet
EP 4650780 A22025-11-193286P54709Espacenet
JP 2025529142 A2025-09-04503P54709Espacenet
US 12384828 B22025-08-12210P54709Espacenet
US 12371689 B22025-07-29503P54709Espacenet
EP 4572801 A12025-06-25315P54709Espacenet
EP 4572802 A12025-06-25315P54709Espacenet
EP 4572803 A12025-06-25315P54709Espacenet
JP 2025517970 A2025-06-123286P54709Espacenet
JP 2025062604 A2025-04-147557P54709Espacenet

1 to 10 of 105

See all 105 patents

Drugs6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACETYLDIGITOXINCHEMBL3545057Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DESLANOSIDECHEMBL1614Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DIGITOXINCHEMBL254219Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
DIGOXINCHEMBL1751Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
ISTAROXIMECHEMBL2093999Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL
LANATOSIDE CCHEMBL506569Sodium/potassium-transporting ATPase inhibitorINHIBITORChEMBL

Trials55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants566

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATP1B3 papersNewest fiscal year
P30CA068485Cancer Center Support Grant72025
U24CA224309Stanford Cancer Immune Monitoring and Analysis Center (CIMAC)52025
P30CA008748Cancer Center Support Grant42025
U19AI104209Integrated Genomic and Functional Studies of Immunotherapy for Multi-Food Allergy42025
U19AI116484Stanford/UNC Biomimetic U19 Research Center42025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
T32CA009054A Training Program for Interdisciplinary Cancer Research32025
K08CA270417Elucidating cancer-intrinsic mechanisms of perineural invasion in pancreatic cancer22025
K08HL159346Deep learning to enable the genetic analysis of aorta22025
P01HL136275Immune Cell Interactions in Atherosclerosis22025

1 to 10 of 566Source NIH's project files

See all 566 nih grants

Papers502

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Glycosylation-Associated Macrophage Signatures Define a Diagnostic Model for Diabetic Retinopathy via Single-Cell Analysis.J Ophthalmol202642662694PubTator, text miningPubMed
ATF4, ZIK1, and PNMA3 Transcriptomic Signatures Predict Chemoradiotherapy Response in Cervical Cancer.Cancer Med202642509645PubTator, text miningPubMed
Identification and molecular typing of disulfidptosis-related biomarkers in anaplastic thyroid carcinoma.Cell Death Discov202642020364PubTator, text miningPubMed
Systematic Druggable Genome-Wide Analysis Identifies Therapeutic Targets for Aging: A Mendelian Randomization Study.Health Sci Rep202642005663PubTator, text miningPubMed
Molecular heterogeneity of HPV-associated cancers and strategies to overcome treatment resistance.Cancer Heterog Plast202641938668PubTator, text miningPubMed
Tumor cell villages define the co-dependency of tumor and microenvironment in liver cancer.Nat Commun202641723121PubTator, text miningPubMed
Spatial transcriptomics identifies IL-32 as a lipid droplet-associated cytokine linked to tubular injury in human diabetic kidney disease.Inflamm Res202641653322PubTator, text miningPubMed
Single-cell spatial transcriptomics uncovers niches that govern response to PD-1/PD-L1 blockade in cutaneous squamous cell carcinoma.J Immunother Cancer202641617396PubTator, text miningPubMed
Development of a unified mass cytometry assay integrating activation-induced markers (AIMs) and cytokine profiling for high-throughput assessment of antigen-specific T cell responses.Hum Vaccin Immunother202641614453PubTator, text miningPubMed
GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast Cancer.Res Sq202641542041PubTator, text miningPubMed

1 to 10 of 502

See all 502 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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