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Gene · 4830

NME1: NME/NM23 nucleoside diphosphate kinase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NME1: NME/NM23 nucleoside diphosphate kinase 1. Genes, record 4830. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4830

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Gene

Symbol
NME1
HGNC
Name
NME/NM23 nucleoside diphosphate kinase 1
HGNC
NCBI Gene ID
4830
NCBI Gene
HGNC ID
HGNC:7849
HGNC
Ensembl
ENSG00000239672
NCBI Gene
Aliases
AWD, GAAD, NB, NBS, NDK1, NDKA, NDPK A, NDPK-A, NDPKA, NM23, NM23-H1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15531Nucleoside diphosphate kinase A15211Ensembl, GeneID, HGNC

Source UniProt

Patents149

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025172739 A2025-11-261781P15531Espacenet
EP 4650780 A22025-11-1911003P15531Espacenet
EP 4641202 A22025-10-295872P15531Espacenet
JP 2025148326 A2025-10-074P15531Espacenet
JP 2025147176 A2025-10-069397P15531Espacenet
US 12415868 B12025-09-161137P15531Espacenet
JP 2025529142 A2025-09-047148P15531Espacenet
US 12371689 B22025-07-297148P15531Espacenet
JP 2025517970 A2025-06-1211003P15531Espacenet
JP 2025028160 A2025-02-289397P15531Espacenet

1 to 10 of 149

See all 149 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,673

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNME1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant142025
P30CA016672Cancer Center Support Grant142025
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases122025
T32CA154274Training Grant in Cancer Biology122025
P30CA014195Cancer Center Support Grant (CCSG)82025
P30CA016058Cancer Center Support Grant62025
P30CA134274UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT52025
P30CA006973Regional Oncology Research Center42025
P30CA091842Cancer Center Support Grant42025
T32CA009370Cancer Heterogeneity, Immunity, and Microenvironment (CHIME) Training Program42025

1 to 10 of 1,673Source NIH's project files

See all 1,673 nih grants

Papers3,561

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and Validation of an E2F Targets-Related Gene Signature Risk Score Predicting the Prognosis of Patients with Uveal Melanoma.Ocul Oncol Pathol202642553888PubTator, text miningPubMed
Bioinformatics-driven discovery and experimental validation of differentially expressed genes in colorectal adenomas.Mol Biol Rep202642517945PubTator, text miningPubMed
N6-methyladenosine reader YTHDF2 facilitates malignant progression of gallbladder cancer by suppressing NME1 expression.Cancer Lett202642498073PubTator, text miningPubMed
Retraction Note: Roles of KAI1 and nm23 in lymphangiogenesis and lymph metastasis of laryngeal squamous cell carcinoma.World J Surg Oncol202642415073PubTator, text miningPubMed
IRX1 suppresses breast cancer progression by inhibiting fatty acid de novo synthesis through downregulating ACACA expression.Cell Death Dis202642225620PubTator, text miningPubMed
Zerumbone Induces Apoptosis and Inhibits Migration of A2058 Melanoma stem-like Cells by Producing Reactive Oxygen Species, Causing G2/M Cell Cycle Arrest, and Controlling the Expression of Genes Linked to Metastasis.
Indian J Clin Biochem202642205222PubTator, text miningPubMed
Oncogenic DCTPP1/MYC feedback loop rewires pyrimidine metabolism to drive hepatocellular carcinoma.Funct Integr Genomics202642062634PubTator, text miningPubMed
Histidine phosphorylation of NME1 regulates the Hippo pathway via the ARHGAP17-CDC42-cytoskeleton axis.Life Med202641978798PubTator, text miningPubMed
Exploring EBNA3C Genetic Variability and Recombination in Epstein-Barr Virus-Associated Cancers.Int J Mol Sci202641977241PubTator, text miningPubMed
Emerging LncRNA HOTAIR and NME1 polymorphisms in ovarian cancer risk: A pilot case-control study in South Indian women.Clin Chim Acta202641921725PubTator, text miningPubMed

1 to 10 of 3,561

See all 3,561 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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