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Gene · 4831

NME2: NME/NM23 nucleoside diphosphate kinase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NME2: NME/NM23 nucleoside diphosphate kinase 2. Genes, record 4831. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4831

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Gene

Symbol
NME2
HGNC
Name
NME/NM23 nucleoside diphosphate kinase 2
HGNC
NCBI Gene ID
4831
NCBI Gene
HGNC ID
HGNC:7850
HGNC
Ensembl
ENSG00000243678
NCBI Gene
Aliases
NDK2, NDKB, NDPK B, NDPK-B, NDPKB, NM23-H2, NM23B, PUF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22392Nucleoside diphosphate kinase B1528Ensembl, GeneID, HGNC

Source UniProt

Patents176

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455885P22392Espacenet
JP 2026004568 A2026-01-1455886P22392Espacenet
JP 2026004568 A2026-01-1455887P22392Espacenet
JP 2026004568 A2026-01-1455888P22392Espacenet
JP 2026004568 A2026-01-1455889P22392Espacenet
EP 4641202 A22025-10-295870P22392Espacenet
US 12415868 B12025-09-1619P22392Espacenet
US 12415868 B12025-09-16200P22392Espacenet
US 12415868 B12025-09-16202P22392Espacenet
JP 2025529142 A2025-09-047149P22392Espacenet

1 to 10 of 176

See all 176 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,206

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNME2 papersNewest fiscal year
T32CA154274Training Grant in Cancer Biology92025
ZIAES050165Structural Studies Of Post-Transcriptional Gene Regulation92025
P30CA008748Cancer Center Support Grant82025
P30CA014195Cancer Center Support Grant (CCSG)72025
P30CA016087Cancer Center Support Grant52025
T32CA009370Cancer Heterogeneity, Immunity, and Microenvironment (CHIME) Training Program42025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant32025
P30CA134274UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT32025
P40OD010440Caenorhabditis Genetics Center32025
R01GM085319Function of Sequence-specific RNA Binding Proteins32025

1 to 10 of 1,206Source NIH's project files

See all 1,206 nih grants

Papers1,736

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dual Randomness From Spatial and Temporal Variations in Stochastic Zinc Gallate Nanoclusters for PUF and TRNG Co-Driven Image Generation.Adv Sci (Weinh)202642806503PubTator, text miningPubMed
Author Correction: Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins.Nat Commun202642586987PubTator, text miningPubMed
NME3 promotes clear cell renal cell carcinoma progression and modulates TKI response through MFN1/2-dependent mitochondrial fusion and mitophagy suppression.Oncogene202642432330PubTator, text miningPubMed
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite.Antimicrob Agents Chemother202642363837PubTator, text miningPubMed
Heterologous expression of lipase gene in Cereibacter sphaeroides 2.4.1 driven by an anaerobic Photosynthesis-Inducible promoter.J Genet Eng Biotechnol202642309595PubTator, text miningPubMed
Stearoyl-CoA desaturase 5 (SCD5) in lipid remodeling: From molecular control to pathophysiology.J Lipid Res202642285304PubTator, text miningPubMed
Pharmacological evaluation of an ex vivo cervicovaginal HIV prevention model.J Antimicrob Chemother202641873439PubTator, text miningPubMed
Quantum Chemical Study of the Formation Mechanism of 5-Substituted N-Methylthiophen-2-amine and N-Methyl-1H-pyrrol-2-thiol from Allenylimidothioates.J Org Chem202641871275PubTator, text miningPubMed
The Potential Molecular Mechanisms and Key Genes of Early Deterioration of Parenchymal Lesions in Cerebral Venous Sinus Thrombosis.Curr Neurovasc Res202641863408PubTator, text miningPubMed
Systematic identification of variant-specific RNA structure-small molecule interactions exemplified by RNA G-quadruplexes.Nat Commun202641857008PubTator, text miningPubMed

1 to 10 of 1,736

See all 1,736 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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