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Gene · 4841

NONO: non-POU domain containing octamer binding

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NONO: non-POU domain containing octamer binding. Genes, record 4841. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4841

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Gene

Symbol
NONO
HGNC
Name
non-POU domain containing octamer binding
HGNC
NCBI Gene ID
4841
NCBI Gene
HGNC ID
HGNC:7871
HGNC
Ensembl
ENSG00000147140
NCBI Gene
Aliases
MRXS34, NMT55, NRB54, P54, P54NRB, PPP1R114, p54(NRB)
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15233Non-POU domain-containing octamer-binding protein4719Ensembl, GeneID, HGNC

Source UniProt

Patents67

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455902Q15233Espacenet
JP 2026004568 A2026-01-1455903Q15233Espacenet
JP 2026004568 A2026-01-1455904Q15233Espacenet
EP 4650780 A22025-11-192961Q15233Espacenet
JP 2025147176 A2025-10-0615407Q15233Espacenet
JP 2025517970 A2025-06-122961Q15233Espacenet
JP 2025028160 A2025-02-2815407Q15233Espacenet
KR 1020250010750 A2025-01-2115407Q15233Espacenet
JP 2024109657 A2024-08-1415246Q15233Espacenet
US 11946082 B22024-04-0215Q15233Espacenet

1 to 10 of 67

See all 67 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,250

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNONO papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene82025
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer72025
P30CA016672Cancer Center Support Grant62025
P50CA217694SPORE in Soft Tissue Sarcoma62025
ZIABC011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene62025
P30CA016058Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
ZIDBC011089Clinical Nursing and Data Management Core52025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer42025

1 to 10 of 1,250Source NIH's project files

See all 1,250 nih grants

Papers2,010

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A TERRA-NONO axis drives fibroblast reprogramming in cancer.Sci Adv202642826195PubTator, text miningPubMed
Epigenetic regulation of DPP4 receptor expression by NONO enables replication of MERS-CoV.bioRxiv202642818199PubTator, text miningPubMed
Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein.Protein Sci202642765842PubTator, text miningPubMed
Clinical Outcomes, Treatment Patterns, and Molecular Heterogeneity of TFE3-Rearranged Renal Cell Carcinoma: A Multicenter Real-World Study.Cancer Med202642726730PubTator, text miningPubMed
Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1-JUN/FOS Axis.Adv Sci (Weinh)202642725805PubTator, text miningPubMed
CDK12/13 inhibition overcomes platinum resistance by impairing RNA metabolism.Signal Transduct Target Ther202642686681PubTator, text miningPubMed
RNA decay rate as a control point for long non-coding RNA function: a BRIC-based causal analysis of NEAT1.Gene202642628853PubTator, text miningPubMed
The paraspeckle protein NONO potentiates the antiviral innate immune response through chromatin regulation.bioRxiv202642523448PubTator, text miningPubMed
Acyclic artificial nucleic acid substitution expands the safe design space of gapmer ASOs by preventing P54nrb mislocalization.NAR Mol Med202642482706PubTator, text miningPubMed
Heart Transplant for Noncompaction Cardiomyopathy in NONO-Related Syndromic Intellectual Disability.Mol Genet Genomic Med202642444102PubTator, text miningPubMed

1 to 10 of 2,010

See all 2,010 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4841

GET https://conductscience.org/api/genes/v1/4841/patents?page=2