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Gene · 4856

CCN3: cellular communication network factor 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CCN3: cellular communication network factor 3. Genes, record 4856. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4856

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Gene

Symbol
CCN3
HGNC
Name
cellular communication network factor 3
HGNC
NCBI Gene ID
4856
NCBI Gene
HGNC ID
HGNC:7885
HGNC
Ensembl
ENSG00000136999
NCBI Gene
Aliases
IBP-9, IGFBP-9, IGFBP9, NOV, NOVh
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P48745CCN family member 33570Ensembl, GeneID, HGNC

Source UniProt

Patents51

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4743106 A12026-05-201P48745Espacenet
JP 2026004568 A2026-01-1455183P48745Espacenet
EP 4650780 A22025-11-191752P48745Espacenet
JP 2025147176 A2025-10-069438P48745Espacenet
JP 2025529142 A2025-09-047159P48745Espacenet
US 12371689 B22025-07-297159P48745Espacenet
JP 2025517970 A2025-06-121752P48745Espacenet
JP 2025028160 A2025-02-289438P48745Espacenet
KR 1020250010750 A2025-01-219438P48745Espacenet
JP 2024109657 A2024-08-149445P48745Espacenet

1 to 10 of 51

See all 51 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants769

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCCN3 papersNewest fiscal year
R01CA107469Role of EZH2 in Breast Cancer Progression72025
P50CA180995SPORE in Prostate Cancer62025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202852025
T32CA009560Carcinogenesis Training Program52025
P20GM103408Idaho INBRE Program32025
P20GM121322Tumor Microenvironment-TME CoBRE32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30DK056338Texas Medical Center Digestive Diseases Center32025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal32025
T32DK007169NW University Program in Endo Diabetes and Hormone Action32025

1 to 10 of 769Source NIH's project files

See all 769 nih grants

Papers1,355

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Calcium dysregulation amplifies fibrotic responses to TGFβ in human Friedreich's ataxia fibroblasts.bioRxiv202642818031PubTator, text miningPubMed
Comprehensive Spatial Transcriptomic Profiling of Cribriform, Intraductal, Atypical Intraductal Proliferation, and Ductal Adenocarcinoma of the Prostate.Lab Invest202642468875PubTator, text miningPubMed
The Relationship Between CCN3 and Rheumatoid Arthritis and Its Potential Therapeutic Value.J Immunol Res202642402859PubTator, text miningPubMed
A working model for CCN3 C-terminal domain-mediated transcriptional modulation of the plasminogen activation system.J Cell Commun Signal202642338747PubTator, text miningPubMed
Prenatal metabolic adversity reprograms insulin-responsive transcription in the developing nucleus accumbens.Mol Metab202642320794PubTator, text miningPubMed
Species-specific roles of cellular communication network proteins in cartilage development: A comparative study using in vitro chondrogenic models.J Cell Commun Signal202642256527PubTator, text miningPubMed
WNT2B impairs endosomal trafficking via WASHC5 to inhibit autophagy: a novel non-secretory WNT pathway.Autophagy202642233622PubTator, text miningPubMed
The Role of the Cellular Communication Network Protein Family in Pulmonary Arterial Hypertension.Pulm Circ202642146788PubTator, text miningPubMed
Tumor-derived GDF15 induces CCN3⁺ Schwann cells to promote cancer pain in pancreatic cancer.Nat Commun202642120379PubTator, text miningPubMed
From early-onset asthma to chronic obstructive pulmonary disease: potential mediating proteins and therapeutic targets.Brief Bioinform202642089751PubTator, text miningPubMed

1 to 10 of 1,355

See all 1,355 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4856

GET https://conductscience.org/api/genes/v1/4856/patents?page=2