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NPHS1: NPHS1 adhesion molecule, nephrin

1 protein, 36 patents, 0 drugs, 0 trials, 1,674 NIH grants and 4,689 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNPHS1HGNC
NameNPHS1 adhesion molecule, nephrinHGNC
NCBI Gene ID4868NCBI Gene
HGNC IDHGNC:7908HGNC
EnsemblENSG00000161270NCBI Gene
AliasesCNF, NPHN, nephrinNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O60500Nephrin1,2411Ensembl, GeneID, HGNCUniProt

Patents 36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026185435 A12026-09-1014O60500Espacenet
EP 4803903 A12026-09-0914O60500Espacenet
EP 4803904 A12026-09-0914O60500Espacenet
JP 2026004568 A2026-01-1455197O60500Espacenet
EP 4650780 A22025-11-1910106O60500Espacenet
EP 4641201 A22025-10-2910398O60500Espacenet
JP 2025147176 A2025-10-069456O60500Espacenet
JP 2025529142 A2025-09-042878O60500Espacenet
JP 2025529142 A2025-09-047163O60500Espacenet
US 12371689 B22025-07-292878O60500Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1674

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK076077Adaptive and maladaptive repair after kidney injury142,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)82,025NIH's project files
U54CA196519Developmental and Hyperactive Ras Tumor (DHART) SPORE62,025NIH's project files
P30DK020579Diabetes Research Center52,025NIH's project files
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair52,025NIH's project files
R01DK104753Crosstalk Between Lipid Droplets and Other Organelles in Podocytes52,025NIH's project files
I01BX004024Transport and metabolism in the kidney42,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)42,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center42,025NIH's project files

Papers 4689

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821141PubTator, text miningPubMed
42813832PubTator, text miningPubMed
42795226PubTator, text miningPubMed
42770105PubTator, text miningPubMed
42768826PubTator, text miningPubMed
42767610PubTator, text miningPubMed
42760000PubTator, text miningPubMed
42709576PubTator, text miningPubMed
42688926PubTator, text miningPubMed
42646582PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license