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NPPB: natriuretic peptide B

1 protein, 229 patents, 0 drugs, 0 trials, 5,785 NIH grants and 32,501 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNPPBHGNC
Namenatriuretic peptide BHGNC
NCBI Gene ID4879NCBI Gene
HGNC IDHGNC:7940HGNC
EnsemblENSG00000120937NCBI Gene
AliasesBNP, Iso-ANPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P16860Natriuretic peptides B1342Ensembl, GeneID, HGNCUniProt

Patents 229

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026082837 A2026-05-1934P16860Espacenet
JP 2026513515 A2026-04-284P16860Espacenet
WO 2026017877 A12026-01-222P16860Espacenet
EP 4680970 A12026-01-214P16860Espacenet
EP 4650780 A22025-11-199779P16860Espacenet
JP 2025169942 A2025-11-141176P16860Espacenet
EP 4641201 A22025-10-2910035P16860Espacenet
JP 2025147176 A2025-10-069471P16860Espacenet
JP 2025529142 A2025-09-047166P16860Espacenet
US 12371689 B22025-07-297166P16860Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5785

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001863Yale Clinical and Translational Science Award582,025NIH's project files
P30CA008748Cancer Center Support Grant362,025NIH's project files
ZIAHL006001Framingham Project/Levy352,025NIH's project files
P30AG021332Wake Forest Claude D. Pepper OAIC - Renewal312,025NIH's project files
UL1TR001881UCLA Clinical and Translational Science Institute202,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
R01HL084155Human Cardiorenal Syndrome192,025NIH's project files
T32HL007111Cardiovasology192,025NIH's project files
T32HL007604Training Grant in Cardiovascular Research182,025NIH's project files
U54GM115428Mississippi Center for Clinical and Translational Research182,025NIH's project files

Papers 32501

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818772PubTator, text miningPubMed
42813127PubTator, text miningPubMed
42808704PubTator, text miningPubMed
42807205PubTator, text miningPubMed
42795793PubTator, text miningPubMed
42793073PubTator, text miningPubMed
42787384PubTator, text miningPubMed
42783512PubTator, text miningPubMed
42783067PubTator, text miningPubMed
42780742PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license