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NRAS: NRAS proto-oncogene, GTPase

1 protein, 377 patents, 1 drug, 0 trials, 7,942 NIH grants and 26,678 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNRASHGNC
NameNRAS proto-oncogene, GTPaseHGNC
NCBI Gene ID4893NCBI Gene
HGNC IDHGNC:7989HGNC
EnsemblENSG00000213281NCBI Gene
AliasesALPS4, CMNS, N-ras, NCMS, NRAS1, NS6, RALD1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01111GTPase NRas18935Ensembl, GeneID, HGNCUniProt

Patents 377

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4825362 A12026-10-2146P01111Espacenet
EP 4805358 A12026-09-165P01111Espacenet
EP 4803075 A12026-09-0946P01111Espacenet
WO 2026121966 A22026-06-116P01111Espacenet
EP 4754118 A12026-06-109P01111Espacenet
JP 2026086799 A2026-05-261P01111Espacenet
JP 2026515740 A2026-05-192P01111Espacenet
EP 4739661 A12026-05-133P01111Espacenet
US 12606572 B22026-04-215P01111Espacenet
EP 4724445 A12026-04-155P01111Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
SALIRASIBCHEMBL23293RAS inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7942

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant5552,025NIH's project files
P30CA016672Cancer Center Support Grant5202,025NIH's project files
P30CA016058Cancer Center Support Grant872,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant782,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program772,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant772,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)692,025NIH's project files
P30CA006973Regional Oncology Research Center662,025NIH's project files
P30CA068485Cancer Center Support Grant622,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award622,025NIH's project files

Papers 26678

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825158PubTator, text miningPubMed
42824995PubTator, text miningPubMed
42821569PubTator, text miningPubMed
42821536PubTator, text miningPubMed
42814135PubTator, text miningPubMed
42809935PubTator, text miningPubMed
42809340PubTator, text miningPubMed
42805360PubTator, text miningPubMed
42802443PubTator, text miningPubMed
42797500PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license