Gene · 4900
NRGN: neurogranin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NRGN: neurogranin. Genes, record 4900. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4900
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q92686 | Neurogranin | 78 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents73
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12560619 B2 | 2026-02-24 | 21 | Q92686 | Espacenet |
| EP 4679096 A1 | 2026-01-14 | 30 | Q92686 | Espacenet |
| EP 4679096 A1 | 2026-01-14 | 31 | Q92686 | Espacenet |
| EP 4679096 A1 | 2026-01-14 | 33 | Q92686 | Espacenet |
| EP 4679096 A1 | 2026-01-14 | 36 | Q92686 | Espacenet |
| EP 4679097 A1 | 2026-01-14 | 30 | Q92686 | Espacenet |
| EP 4679097 A1 | 2026-01-14 | 31 | Q92686 | Espacenet |
| EP 4679097 A1 | 2026-01-14 | 33 | Q92686 | Espacenet |
| EP 4679097 A1 | 2026-01-14 | 36 | Q92686 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55442 | Q92686 | Espacenet |
1 to 10 of 73
See all 73 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,780
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NRGN papers | Newest fiscal year |
|---|---|---|---|
| R01AG027161 | Wisconsin Registry for Alzheimer's Prevention | 24 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 21 | 2025 |
| R01AG021155 | The Longitudinal Course of Imaging Biomarkers in People At Risk for Alzheimer’s Disease | 21 | 2025 |
| P20GM109025 | Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - Resubmission | 20 | 2025 |
| P30AG062715 | Wisconsin Alzheimer's Disease Research Center | 20 | 2025 |
| P30AG066444 | Alzheimer's Disease Research Center | 17 | 2025 |
| U19AG032438 | Bridge Funding for Dominantly Inherited Alzheimer Network | 11 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 10 | 2025 |
| P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 7 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 7 | 2025 |
1 to 10 of 1,780Source NIH's project files
See all 1,780 nih grantsPapers2,084
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Dynamic changes in plasma biomarkers of Alzheimer's disease in patients treated with lecanemab: a longitudinal cohort study. | Lancet Neurol | 2026 | 42785333 | PubTator, text mining | PubMed |
| Proteomic markers linking anxiety phenotypes to Alzheimer's disease risk: a multi-analyte proteomic analysis. | medRxiv | 2026 | 42779925 | PubTator, text mining | PubMed |
| Altered synaptic and astrocytic proteins in Lewy body disorders associated with GBA mutations. | Brain Commun | 2026 | 42582587 | PubTator, text mining | PubMed |
| Semaglutide as a potential neuroprotective agent for neurological and neurodegenerative disorders: Mechanisms, preclinical evidence, and translational challenges and opportunities. | Mol Biol Rep | 2026 | 42573665 | PubTator, text mining | PubMed |
| Harnessing Affinity Tags for Recombinant Protein Purification: Concepts, Methods, and Troubleshooting. | Methods Mol Biol | 2026 | 42562985 | PubTator, text mining | PubMed |
| Biochemical modulators of synaptic plasticity: New horizons in Alzheimer's disease treatment. | J Alzheimers Dis | 2026 | 42489531 | PubTator, text mining | PubMed |
| NRGN inhibits CD8⁺ T cell effector function by downregulating MHC-I expression through the FMR1-IRF8 axis in hepatocellular carcinoma. | J Exp Clin Cancer Res | 2026 | 42458540 | PubTator, text mining | PubMed |
| Higher physical activity levels mitigate synaptic protein loss and cognitive deterioration in aging and in Alzheimer's disease: a 10-year longitudinal study. | Mol Biomed | 2026 | 42455424 | PubTator, text mining | PubMed |
| Glial molecular signatures as a liquid biopsy marker in Alzheimer's disease diagnosis. | Int Rev Neurobiol | 2026 | 42442917 | PubTator, text mining | PubMed |
| Value of synaptic proteins as biomarkers in amyotrophic lateral sclerosis. | Brain Commun | 2026 | 42404435 | PubTator, text mining | PubMed |
1 to 10 of 2,084
See all 2,084 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4900
GET https://conductscience.org/api/genes/v1/4900/patents?page=2