Gene · 4905
NSF: N-ethylmaleimide sensitive factor, vesicle fusing ATPase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NSF: N-ethylmaleimide sensitive factor, vesicle fusing ATPase. Genes, record 4905. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4905
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P46459 | Vesicle-fusing ATPase | 744 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4689130 A2 | 2026-02-11 | 132 | P46459 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55212 | P46459 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11577 | P46459 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12144 | P46459 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 12144 | P46459 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11577 | P46459 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55904 | P46459 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55911 | P46459 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55912 | P46459 | Espacenet |
| US 11371991 B2 | 2022-06-28 | 1 | P46459 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,862
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NSF papers | Newest fiscal year |
|---|---|---|---|
| R35GM118037 | Mechanisms of Membrane Fusion | 11 | 2025 |
| R01MH063105 | Molecular mechanisms of synaptic neurotransmitter release | 8 | 2025 |
| R01HL016037 | Molecular Regulation of Cardiovascular 7 TM Receptors | 6 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 4 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| R01GM083144 | Characterization of mammalian COG complex-interacting Golgi trafficking machinery | 4 | 2025 |
| R01HD038082 | Sperm Ca2+ signaling and energy pathways in basic science and ART | 4 | 2025 |
1 to 10 of 1,862Source NIH's project files
See all 1,862 nih grantsPapers1,983
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Elucidating shared genetic signals between type 2 diabetes and three neurodegenerative dementia phenotypes. | HGG Adv | 2026 | 42681870 | PubTator, text mining | PubMed |
| NSF gene variants cause developmental and epileptic encephalopathy 96: expanding genotype and phenotypic spectrum with prenatal-onset features. | Front Genet | 2026 | 42609877 | PubTator, text mining | PubMed |
| Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output. | Cold Spring Harb Perspect Biol | 2026 | 42575696 | PubTator, text mining | PubMed |
| Supervised Exercise Intervention Restores Physical Activity and MultiOMIC-Derived Frailty Biomarkers in Older Adults. | J Cachexia Sarcopenia Muscle | 2026 | 42571782 | PubTator, text mining | PubMed |
| Characterizing the impact of plasma protein levels on human brain structure and disorders leveraging integrative multi-omics analysis. | medRxiv | 2026 | 42528609 | PubTator, text mining | PubMed |
| A vesicular trafficking pathway mediated by N-ethylmaleimide-sensitive factor governs integrin maturation and podocyte integrity. | Kidney Int | 2026 | 42492856 | PubTator, text mining | PubMed |
| Integrative multi-omics analysis identifies a mitochondrial dysfunction-associated diagnostic signature, molecular subtypes, and drug repurposing candidates for keloid disease. | Burns | 2026 | 42413388 | PubTator, text mining | PubMed |
| HiFiMAP: High-resolution fast identity-by-descent mapping test. | medRxiv | 2026 | 42180323 | PubTator, text mining | PubMed |
| The RBFOX1 regulatory gene network contributes to major depressive disorder, anxiety, irritability and neuroticism. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42034278 | PubTator, text mining | PubMed |
| NSF is required for diverse endocytic modes by promoting fusion and fission pore closure in secretory cells. | iScience | 2026 | 42004027 | PubTator, text mining | PubMed |
1 to 10 of 1,983
See all 1,983 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4905
GET https://conductscience.org/api/genes/v1/4905/patents?page=2