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Gene · 4909

NTF4: neurotrophin 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NTF4: neurotrophin 4. Genes, record 4909. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4909

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Gene

Symbol
NTF4
HGNC
Name
neurotrophin 4
HGNC
NCBI Gene ID
4909
NCBI Gene
HGNC ID
HGNC:8024
HGNC
Ensembl
ENSG00000225950
NCBI Gene
Aliases
GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P34130Neurotrophin-42103Ensembl, GeneID, HGNC

Source UniProt

Patents116

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4762080 A12026-06-245P34130Espacenet
EP 4705273 A22026-03-11256P34130Espacenet
JP 2026004568 A2026-01-1455601P34130Espacenet
JP 2026000906 A2026-01-06256P34130Espacenet
EP 4650780 A22025-11-1917856P34130Espacenet
JP 2025147176 A2025-10-069613P34130Espacenet
JP 2025529142 A2025-09-047188P34130Espacenet
US 12371689 B22025-07-297188P34130Espacenet
JP 2025517970 A2025-06-1217856P34130Espacenet
JP 2025028160 A2025-02-289613P34130Espacenet

1 to 10 of 116

See all 116 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,135

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNTF4 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
R01EY023557Primary Open Angle African-American Glaucoma Genetics Study Renewal42025
R01HL056470Neonatal Modulation of Airway Contractility42025
UG1HD034216NICHD Neonatal Research Network Clinical Center UAB42025
P30EY001583P30 Core Grant For Vision Research32025
P30EY001792P30 Core Grant for Vision Research32025
P30EY016665Core Grant for Vision Research32025
R01HD041702Preterm Birth and Child Long-term Cardiometabolic Risk: Integrate Proteomics with Birth Cohort32025
T32HL007035Biology of the Lung: A Multidisciplinary Program32025
P20GM103436IDeA Networks of Biomedical Research Excellence in Kentucky22025

1 to 10 of 1,135Source NIH's project files

See all 1,135 nih grants

Papers2,282

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Shared genetic architecture of schizophrenia and lupus identifies pleiotropic loci with distinct downstream mechanisms.Hum Mol Genet202642822865PubTator, text miningPubMed
Genetic Architecture and Clinical Phenotypes of Primary Open-Angle Glaucoma: An Updated Review of Mendelian Genes, GWAS Loci, and Polygenic Risk.Clin Ophthalmol202642751619PubTator, text miningPubMed
Brain-derived neurotrophic factor (BDNF) in neonatal blood: associations with respiratory disease in extremely preterm infants.Pediatr Res202642567895PubTator, text miningPubMed
Large-Scale Plasma Proteomics Profiles for Predicting Atrial Fibrillation Associated Stroke Risk : Type of manuscript: Original Research.Transl Stroke Res202642489810PubTator, text miningPubMed
N-Isocaproyl-L-Arginylglycine Hexamethylenediamide, First Low-Molecular-Weight Mimetic of Neurotrophin-4: Design and Neuroprotective Activity.Dokl Biol Sci202642443573PubTator, text miningPubMed
Aqueous Humor Cytokine Profiles in Congenital Cataracts With Posterior Polar Abnormality and Associations With Postoperative Complications.Invest Ophthalmol Vis Sci202642132464PubTator, text miningPubMed
Inhibition of NTF4 Attenuates High Glucose-Induced Apoptosis and Inflammation in HTR-8/SVneo Cells via the PI3K/AKT Pathway.Immun Inflamm Dis202642036822PubTator, text miningPubMed
Causal Relationship Between Neurotrophins and Normal Pressure Hydrocephalus: Insights From a Bidirectional Two-Sample Mendelian Randomization Study.Brain Behav202641913636PubTator, text miningPubMed
Role of Growth Hormone (GH) and Other Somatotropic Axis Elements in Retinal Neuroprotection.Curr Issues Mol Biol202641899448PubTator, text miningPubMed
Neurotrophins Plasma Levels Kinetics in Ischemic Stroke Patients-Potential Relation to Outcomes.Neurol Int202641893053PubTator, text miningPubMed

1 to 10 of 2,282

See all 2,282 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4909

GET https://conductscience.org/api/genes/v1/4909/patents?page=2