Gene · 4913
NTHL1: nth like DNA glycosylase 1
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. NTHL1: nth like DNA glycosylase 1. Genes, record 4913. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4913
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78549 | Endonuclease III-like protein 1 | 304 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents3
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants856
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NTHL1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 26 | 2025 |
| U01CA167551 | Colon Cancer Family Registry Cohort | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 9 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 8 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 856Source NIH's project files
See all 856 nih grantsPapers1,281
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional impact of Nth like DNA glycosylase 1 on mitochondrial dynamics. | Nucleic Acids Res | 2026 | 42741840 | PubTator, text mining | PubMed |
| Collaborations with Miral Dizdaroglu: expanding on connections between oxidative DNA damage and aging and disease. | Int J Radiat Biol | 2026 | 42573227 | PubTator, text mining | PubMed |
| Universally offered germline testing in upper tract urothelial carcinoma. | Urol Oncol | 2026 | 42542401 | PubTator, text mining | PubMed |
| A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad. | Nat Commun | 2026 | 42457729 | PubTator, text mining | PubMed |
| Universal Germline Genetic Testing in a Precision Oncology and Rare Cancer Clinic: Implementation and Outcomes. | JCO Oncol Adv | 2026 | 42422224 | PubTator, text mining | PubMed |
| Biochemical, structural and mutational landscapes of base excision repair enzymes and cancer: from atomic resolution to tumor signatures. | Int J Radiat Biol | 2026 | 42378620 | PubTator, text mining | PubMed |
| Benign Neoplasms in Biallelic Nth-Like DNA Glycosylase 1-Associated Tumor Syndrome: Expanding the Clinical Phenotype. | ACG Case Rep J | 2026 | 42326453 | PubTator, text mining | PubMed |
| Monoallelic NTHL1 p.(Gln90*) and cancer risk: evidence from a large Turkish cohort. | Fam Cancer | 2026 | 42319512 | PubTator, text mining | PubMed |
| Hereditary Cancer Genetic Testing for All? A Retrospective Analysis on Genetic Mutations Found in Individuals Not Meeting NCCN® Guidelines. | Eur J Breast Health | 2026 | 42317085 | PubTator, text mining | PubMed |
| The Landscape of Genomic and Socioeconomic Variables in Patients with Colorectal Cancer Based on Genetic Ancestry. | Cancer Epidemiol Biomarkers Prev | 2026 | 42084482 | PubTator, text mining | PubMed |
1 to 10 of 1,281
See all 1,281 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4913
GET https://conductscience.org/api/genes/v1/4913/grants?page=2