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Gene · 4920

ROR2: ROR family WNT receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ROR2: ROR family WNT receptor 2. Genes, record 4920. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4920

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Gene

Symbol
ROR2
HGNC
Name
ROR family WNT receptor 2
HGNC
NCBI Gene ID
4920
NCBI Gene
HGNC ID
HGNC:10257
HGNC
Ensembl
ENSG00000169071
NCBI Gene
Aliases
BDB, BDB1, NTRKR2, RRS1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01974Tyrosine-protein kinase transmembrane receptor ROR29436Ensembl, GeneID, HGNC

Source UniProt

Patents60

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026128025 A22026-06-1838Q01974Espacenet
EP 4739347 A12026-05-1338Q01974Espacenet
JP 2026501564 A2026-01-1634Q01974Espacenet
JP 2026004568 A2026-01-1461156Q01974Espacenet
EP 4650780 A22025-11-199670Q01974Espacenet
EP 4642808 A22025-11-0534Q01974Espacenet
EP 4641201 A22025-10-299926Q01974Espacenet
JP 2025137618 A2025-09-1995Q01974Espacenet
JP 2025529142 A2025-09-043768Q01974Espacenet
US 12371689 B22025-07-293768Q01974Espacenet

1 to 10 of 60

See all 60 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,312

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleROR2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant122025
P30CA010815Consolidated Basic Cancer Research Program72025
P30CA076292Moffitt Cancer Center Support Grant52025
P30CA016058Cancer Center Support Grant42025
R01CA204484Novel Enediyne-Based Antibody-Drug Conjugates for Cancers42025
R35GM122485Understanding Signaling by Non-Canonical Receptor Tyrosine Kinases42025
R35NS105078STRUCTURAL VARIATION IN NEUROLOGICAL DISEASE42025
T32CA009171Training Program in Basic Cancer Research42025
T32ES007126Pre- and Postdoctoral Training in Toxicology42025

1 to 10 of 1,312Source NIH's project files

See all 1,312 nih grants

Papers2,066

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Targeting an ASCL1-WNT11-ERK feed-forward loop to overcome pyrotinib resistance in HER2-positive breast cancer.Mater Today Bio202642787995PubTator, text miningPubMed
Composition and Function of Decellularized Human Lung Extracellular Matrix from Congenital Pulmonary Airway Malformation.J Clin Med202642739747PubTator, text miningPubMed
Surface and global proteomics identify ROR2 and other proteins as potentially actionable immunotherapeutic targets in osteosarcoma.Cell Rep202642647168PubTator, text miningPubMed
Paediatric Therapeutic Development Workshop on rhabdomyosarcoma.Br J Cancer202642288687PubTator, text miningPubMed
The multifaceted roles of receptor tyrosine pseudokinases in cellular signalling.Biochem Soc Trans202642267535PubTator, text miningPubMed
MYOD1 mutation drives cancer stem cell pathways and therapy-resistance in spindle cell/sclerosing rhabdomyosarcoma.Nat Commun202642236477PubTator, text miningPubMed
CRI-CCTG-0003/IND.240 an immunotherapy platform study in platinum-resistant high grade serous ovarian cancer (IPROC): Sub-studies A and B: Durvalumab (D) + mecbotamab vedotin (BA3011) or ozuriftamab vedotin (BA3021).
Cancer Treat Res Commun202642225005PubTator, text miningPubMed
Meflin confers antifibrotic properties to intestinal fibroblasts in inflammatory bowel disease.J Clin Invest202642154532PubTator, text miningPubMed
Tiki2 restrains Wnt5a/Ror signaling to limit inflammation in acute kidney injury.Commun Biol202641981279PubTator, text miningPubMed
Human receptive endometrial assembloid for deciphering the implantation window.Elife202641920166PubTator, text miningPubMed

1 to 10 of 2,066

See all 2,066 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4920

GET https://conductscience.org/api/genes/v1/4920/patents?page=2