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DDR2: discoidin domain receptor tyrosine kinase 2
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Gene · 4921

Papers2,653

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,653

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TitleJournalYearPMIDFound bySource
Donor-dependent heterogeneity and matrix-remodeling transcriptional programs in COL2A1-variant urine-derived cell cultures with IGF1-associated cell-state shifts.Front Cell Dev Biol202642745831PubTator, text miningPubMed
Quantitative structural alterations of collagen dictate discoidin domain receptor 2 binding efficacy and CAL-27 cell adhesion behaviors.Int J Biol Macromol202642722254PubTator, text miningPubMed
Vascular adventitial cells and vascular remodeling: when a harp of thousand strings does not keep in tune so long.Front Physiol202642707986PubTator, text miningPubMed
Prominent Myxoid and Collagenous Stromal Patterns in Dedifferentiated Liposarcoma: A Comparative Analysis of Immunophenotypic and Genomic Profiles.Anticancer Res202642674680PubTator, text miningPubMed
Type I collagen matrix signaling in cancer: receptor sensing and mechanotransduction.Cell Signal202642660397PubTator, text miningPubMed
Long Non-Coding RNAs and Circular RNAs in the Pathobiology of T-Cell Lymphoma.Cancers (Basel)202642649850PubTator, text miningPubMed
Roles of integrin β1 and discoidin domain receptor 2 in cranial regeneration and skeletal progenitor cell function.Int J Oral Sci202642613320PubTator, text miningPubMed
Subcellular proteomic analysis of the DDR2 interactome in a neuronal cell model exposed to Aβ42.Biochim Biophys Acta Proteins Proteom202642612957PubTator, text miningPubMed
SERPINH1 expression represents a reliable biomarker of human breast cancer aggressiveness.Biol Direct202642464413PubTator, text miningPubMed
Characterization of white adipocyte heterogeneity using data-driven microscopy.Int J Obes (Lond)202642420601PubTator, text miningPubMed
Colorectal Cancer Liver Metastasis-Associated Ferroptosis-Related Genes Modulate Lipid Peroxidation in Colorectal Cancer Cells.Mol Carcinog202642378631PubTator, text miningPubMed
Preliminary pharmacokinetic investigation of two discoidin domain receptor 2 inhibitors in murine plasma and brain using liquid chromatography-tandem mass spectrometry analysis.Sci Rep202642342854PubTator, text miningPubMed
Quantification of Binding of Small Molecules to Native Kinases by Flow Cytometry Reveals Divergence from Biochemical Affinities.J Am Chem Soc202642336767PubTator, text miningPubMed
Evidence that disruption of Discoidin domain receptor 2 contributes to palate malformations through effects on the extracellular matrix.Hum Mol Genet202642323896PubTator, text miningPubMed
Efficient multi-lineage cardiovascular differentiation of human pluripotent stem cells in animal serum-free conditions.Sci Rep202642304033PubTator, text miningPubMed
Extracellular matrix stiffness determines the phenotypic behavior of dedifferentiated melanoma cells through a DDR1/2-dependent YAP mechanotransduction pathway.Oncogenesis202642288492PubTator, text miningPubMed
Dissecting Discoidin Domain Receptor 2 Dynamics in Fibrosis with a Programmable Collagen-Mimetic Probe.ACS Nano202642246507PubTator, text miningPubMed
DDR2 expression on circulating lymphocytes and monocytes associates with chronic active antibody-mediated rejection in kidney transplant recipients.Transl Androl Urol202642164381PubTator, text miningPubMed
COL10A1 beyond skeletal development: a hypertrophic chondrocyte-specific collagen emerging as a potential biomarker and tumor microenvironment regulator in solid cancers.Am J Cancer Res202642163866PubTator, text miningPubMed
Efficacy of olaparib in advanced cancers with somatic or germline mutations in BAP1, BARD1, BRIP1 and PALB2.ESMO Open202642105598PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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