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Gene · 4922

NTS: neurotensin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NTS: neurotensin. Genes, record 4922. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4922

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Gene

Symbol
NTS
HGNC
Name
neurotensin
HGNC
NCBI Gene ID
4922
NCBI Gene
HGNC ID
HGNC:8038
HGNC
Ensembl
ENSG00000133636
NCBI Gene
Aliases
NMN-125, NN, NT, NT/N, NTS1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30990Neurotensin/neuromedin N17011Ensembl, GeneID, HGNC

Source UniProt

Patents72

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455569P30990Espacenet
EP 4650780 A22025-11-191559P30990Espacenet
EP 4641201 A22025-10-291179P30990Espacenet
JP 2025147176 A2025-10-069643P30990Espacenet
JP 2025529142 A2025-09-047196P30990Espacenet
US 12371689 B22025-07-297196P30990Espacenet
JP 2025517969 A2025-06-121179P30990Espacenet
JP 2025517970 A2025-06-121559P30990Espacenet
JP 2025028160 A2025-02-289643P30990Espacenet
KR 1020250010750 A2025-01-219643P30990Espacenet

1 to 10 of 72

See all 72 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,020

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNTS papersNewest fiscal year
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant82025
P30CA016086Cancer Center Support Grant72025
ZIADK053200Diagnosis, Natural History, Management, tumor biology of Gastrinomas/PETs/Neuroendocrine tumors62025
P30CA008748Cancer Center Support Grant52025
R01DK103808Role of Lateral Hypothalamic Neurotensin Neurons in Energy Balance52025
ZIADK053101Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors52025
P30DA018310Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling42025
R01DK112034Mechanisms Regulating Neurotensin Secretion and Function42025
P30DK020572Michigan Diabetes Research Center (MDRC)32025
R01DK071801Mass Spectrometric Studies of Neuropeptides in Feeding32025

1 to 10 of 1,020Source NIH's project files

See all 1,020 nih grants

Papers2,041

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Mimics of the chordate gut-brain hormone neurotensin in parasitic intestinal hookworms.Curr Biol202642551435PubTator, text miningPubMed
Side effects in hypertension treatment: a pharmacogenomic analysis.Eur Heart J202642545033PubTator, text miningPubMed
Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity.Nat Commun202642486867PubTator, text miningPubMed
Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models.Sci Transl Med202642384771PubTator, text miningPubMed
Expression of the High-affinity Neurotensin Receptor Defines an Immune‑cold, Poor‑prognosis Colorectal Cancer Subtype.Ann Surg202642322125PubTator, text miningPubMed
Impact of intestinal resections on the secretion of gastrointestinal hormones.Clin Nutr202642320379PubTator, text miningPubMed
Neuroimmune Regulation of Microvascular Inflammation: The Heart-Brain Axis, Mast Cells, and the Protective Role of Flavonoids-A Comprehensive Review.Biomedicines202642193398PubTator, text miningPubMed
Improved brain penetration of neurotensin(8-13) via blood-brain barrier shuttle conjugation underlies strong analgesia.Biomed Pharmacother202642176569PubTator, text miningPubMed
Neurotensin Receptor 1 Regulates HER4 Tyrosine Phosphorylation in Lung Cancer Cells.Biology (Basel)202642117825PubTator, text miningPubMed
Dual-target opioid/neurotensin ligands drive potent and safer analgesia in vivo.Biomed Pharmacother202642116252PubTator, text miningPubMed

1 to 10 of 2,041

See all 2,041 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4922

GET https://conductscience.org/api/genes/v1/4922/patents?page=2