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Gene · 4923

NTSR1: neurotensin receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NTSR1: neurotensin receptor 1. Genes, record 4923. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4923

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Gene

Symbol
NTSR1
HGNC
Name
neurotensin receptor 1
HGNC
NCBI Gene ID
4923
NCBI Gene
HGNC ID
HGNC:8039
HGNC
Ensembl
ENSG00000101188
NCBI Gene
Aliases
NTR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30989Neurotensin receptor type 141848Ensembl, GeneID, HGNC

Source UniProt

Patents49

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026062654 A2026-04-1043P30989Espacenet
JP 2026004568 A2026-01-1455572P30989Espacenet
JP 2025529142 A2025-09-042921P30989Espacenet
US 12371689 B22025-07-292921P30989Espacenet
JP 2025032204 A2025-03-1132668P30989Espacenet
EP 4461818 A22024-11-1332668P30989Espacenet
JP 2023156353 A2023-10-2443P30989Espacenet
US 11673938 B22023-06-1310P30989Espacenet
JP 2023058610 A2023-04-2532668P30989Espacenet
US 11446398 B22022-09-2056674P30989Espacenet

1 to 10 of 49

See all 49 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
REMINERTANTCHEMBL506981Neurotensin receptor 1 antagonistANTAGONIST

Source ChEMBL

Trials1

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first posted
NCT00290953REMINERTANTPHASE2/PHASE3

NIH grants1,420

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNTSR1 papersNewest fiscal year
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant82025
P30CA016086Cancer Center Support Grant72025
P30DK020579Diabetes Research Center62025
P30DK056341Washington University Nutrition Obesity Research Center62025
R35GM143054The role of dynamics in GPCR and arrestin allostery52025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease42025
R01DK112034Mechanisms Regulating Neurotensin Secretion and Function42025
R01EY011500Structure-function studies of visual arrestin42025
R01MH112205Molecular Details of Psychoactive Drug Actions42025

1 to 10 of 1,420Source NIH's project files

See all 1,420 nih grants

Papers2,119

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins.bioRxiv202642818085PubTator, text miningPubMed
The TWIST1/NTSR1 Axis Drives Aerobic Glycolysis to Promote Metastasis of Lung Adenocarcinoma Cells.Tohoku J Exp Med202642749628PubTator, text miningPubMed
Immobilization of neurotensin receptor through immunologic recognition between ALFA tag and nanobody for affinity-based ligand discovery.J Chromatogr A202642748893PubTator, text miningPubMed
First Case of Mixed Poorly Differentiated Mucinous Adenocarcinoma and High-Grade Neuroendocrine Neoplasm With Amphicrine Differentiation.Cureus202642732443PubTator, text miningPubMed
Systematic characterization of neurotransmitter receptor dysregulation identifies a neural-related prognostic signature associated with biochemical recurrence in prostate cancer.Transl Androl Urol202642729070PubTator, text miningPubMed
Identification of a novel signature for prognostic stratification and integrative analyses in lung adenocarcinoma.Transl Cancer Res202642724475PubTator, text miningPubMed
Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to p-aminobenzenesulfonamide.Front Bioeng Biotechnol202642548832PubTator, text miningPubMed
Side effects in hypertension treatment: a pharmacogenomic analysis.Eur Heart J202642545033PubTator, text miningPubMed
Cell death analysis of inducible, titratable neurodegenerative disease models in zebrafish and human stem cell-derived retinal organoids.Dis Model Mech202642497345PubTator, text miningPubMed
Cytoplasmic ERβ Localization and NTS/NTSR1 Expression in Uterine Leiomyosarcoma: An Immunohistochemical Insight.Reports (MDPI)202642496496PubTator, text miningPubMed

1 to 10 of 2,119

See all 2,119 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4923

GET https://conductscience.org/api/genes/v1/4923/patents?page=2