Gene · 4923
NTSR1: neurotensin receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NTSR1: neurotensin receptor 1. Genes, record 4923. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4923
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P30989 | Neurotensin receptor type 1 | 418 | 48 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026062654 A | 2026-04-10 | 43 | P30989 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55572 | P30989 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2921 | P30989 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2921 | P30989 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32668 | P30989 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32668 | P30989 | Espacenet |
| JP 2023156353 A | 2023-10-24 | 43 | P30989 | Espacenet |
| US 11673938 B2 | 2023-06-13 | 10 | P30989 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 32668 | P30989 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 56674 | P30989 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| REMINERTANT | CHEMBL506981 | Neurotensin receptor 1 antagonist | ANTAGONIST |
Source ChEMBL
Trials1
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted |
|---|---|---|---|
| NCT00290953 | REMINERTANT | PHASE2/PHASE3 |
Source ClinicalTrials.gov
NIH grants1,420
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NTSR1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 8 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| P30DK020579 | Diabetes Research Center | 6 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 6 | 2025 |
| R35GM143054 | The role of dynamics in GPCR and arrestin allostery | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 4 | 2025 |
| R01DK112034 | Mechanisms Regulating Neurotensin Secretion and Function | 4 | 2025 |
| R01EY011500 | Structure-function studies of visual arrestin | 4 | 2025 |
| R01MH112205 | Molecular Details of Psychoactive Drug Actions | 4 | 2025 |
1 to 10 of 1,420Source NIH's project files
See all 1,420 nih grantsPapers2,119
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins. | bioRxiv | 2026 | 42818085 | PubTator, text mining | PubMed |
| The TWIST1/NTSR1 Axis Drives Aerobic Glycolysis to Promote Metastasis of Lung Adenocarcinoma Cells. | Tohoku J Exp Med | 2026 | 42749628 | PubTator, text mining | PubMed |
| Immobilization of neurotensin receptor through immunologic recognition between ALFA tag and nanobody for affinity-based ligand discovery. | J Chromatogr A | 2026 | 42748893 | PubTator, text mining | PubMed |
| First Case of Mixed Poorly Differentiated Mucinous Adenocarcinoma and High-Grade Neuroendocrine Neoplasm With Amphicrine Differentiation. | Cureus | 2026 | 42732443 | PubTator, text mining | PubMed |
| Systematic characterization of neurotransmitter receptor dysregulation identifies a neural-related prognostic signature associated with biochemical recurrence in prostate cancer. | Transl Androl Urol | 2026 | 42729070 | PubTator, text mining | PubMed |
| Identification of a novel signature for prognostic stratification and integrative analyses in lung adenocarcinoma. | Transl Cancer Res | 2026 | 42724475 | PubTator, text mining | PubMed |
| Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to p-aminobenzenesulfonamide. | Front Bioeng Biotechnol | 2026 | 42548832 | PubTator, text mining | PubMed |
| Side effects in hypertension treatment: a pharmacogenomic analysis. | Eur Heart J | 2026 | 42545033 | PubTator, text mining | PubMed |
| Cell death analysis of inducible, titratable neurodegenerative disease models in zebrafish and human stem cell-derived retinal organoids. | Dis Model Mech | 2026 | 42497345 | PubTator, text mining | PubMed |
| Cytoplasmic ERβ Localization and NTS/NTSR1 Expression in Uterine Leiomyosarcoma: An Immunohistochemical Insight. | Reports (MDPI) | 2026 | 42496496 | PubTator, text mining | PubMed |
1 to 10 of 2,119
See all 2,119 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4923
GET https://conductscience.org/api/genes/v1/4923/patents?page=2