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OAS1: 2'-5'-oligoadenylate synthetase 1
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Gene · 4938

Papers3,817

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,817

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TitleJournalYearPMIDFound bySource
Advances in Cytosolic dsRNA Sensing of Viral Infections.Immunol Cell Biol202642802076PubTator, text miningPubMed
In vitro functional characterization of Tadarida brasiliensis interferon-β: promoter responsiveness, antiviral activity, and JAK-dependent transcriptional responses.Front Immunol202642755578PubTator, text miningPubMed
Different Effects of Acute and Chronic Hypoxia on Antiviral Capacity of Pulmonary Vascular Endothelial Cells.J Immunol Res202642689458PubTator, text miningPubMed
Class I capsid assembly modulators induce potent anti-HBV activity through direct viral suppression, innate immune activation and caspase-3-independent clearance of infected hepatocytes.Antiviral Res202642674237PubTator, text miningPubMed
Integrated Functional Characterization of a Panel of Clinical Orthoflavivirus Isolates Reveals Distinct Replication and Innate Immune Response Profiles in Human Keratinocytes.Viruses202642655646PubTator, text miningPubMed
Interstitial Lung Disease in Children: Rare Genetic Variants Beyond Surfactant Dysfunction.Pediatr Pulmonol202642598967PubTator, text miningPubMed
MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA.Cell Death Differ202642557376PubTator, text miningPubMed
Functional restoration of immune defects in STAT1 gain-of-function disease following stem cell gene editing.Blood202642550765PubTator, text miningPubMed
Temporal Dynamics of Innate Immune Activation and Viral Interference During Sequential Co-Infection with Influenza A Virus and SARS-CoV-2: Molecular Mechanisms, Clinical Evidence, and Therapeutic Implications.
Int J Mol Sci202642450260PubTator, text miningPubMed
Repeated aminoglycoside exposure activates interferon-stimulated genes in human renal proximal tubular models.Arch Toxicol202642446670PubTator, text miningPubMed
Integrated multi-omics analysis reveals tumor-suppressive phenotypes and associated transcriptomic remodeling upon METTL3 overexpression in A549 lung cancer cells.Transl Cancer Res202642445413PubTator, text miningPubMed
Antiviral potential of selenium-enriched Bacillus pumilus: Inhibition of PCV2 replication via alleviation of oxidative stress.J Appl Microbiol202642435041PubTator, text miningPubMed
Integration of single-cell cis-expression quantitative trait locus and Mendelian randomization analyses identifies a Treg-specific gene for precision therapy in rheumatoid arthritis, gonarthrosis, and gouty arthritis.
J Int Med Res202642343651PubTator, text miningPubMed
Baicalein activates the type I interferon signaling pathway to inhibit infectious bronchitis virus infection.Poult Sci202642335779PubTator, text miningPubMed
Parimifasor elicits broad-spectrum antitumor effects by suppressing the expression of oncogenic genes.Transl Cancer Res202642305505PubTator, text miningPubMed
African swine fever virus pM448R protein promotes STUB1-mediated ubiquitin-proteasome degradation of IRF1 to attenuate type III interferon induction.J Virol202642262133PubTator, text miningPubMed
BVDV hijacks the IDO1-dependent tryptophan-kynurenine axis to promote viral replication by limiting interferon-STAT1 antiviral signaling.Vet Microbiol202642241958PubTator, text miningPubMed
The OAS1-FASN axis promotes pancreatic cancer by coordinating lipogenic stress and the unfolded protein response.Cell Death Dis202642236684PubTator, text miningPubMed
Re Du Ning exerts anti-influenza activity by counteracting viral NS1-mediated suppression of host type I interferon signaling.J Ethnopharmacol202642235715PubTator, text miningPubMed
The porcine-derived compound Bacillus alleviates piglet infection with porcine epidemic diarrhea virus by reshaping the intestinal barrier and microbial balance.Microb Pathog202642235708PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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