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Gene · 4940

OAS3: 2'-5'-oligoadenylate synthetase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. OAS3: 2'-5'-oligoadenylate synthetase 3. Genes, record 4940. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4940

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Gene

Symbol
OAS3
HGNC
Name
2'-5'-oligoadenylate synthetase 3
HGNC
NCBI Gene ID
4940
NCBI Gene
HGNC ID
HGNC:8088
HGNC
Ensembl
ENSG00000111331
NCBI Gene
Aliases
p100, p100OAS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y6K52'-5'-oligoadenylate synthase 31,0871Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1435696Q9Y6K5Espacenet
EP 4640849 A22025-10-2987Q9Y6K5Espacenet
EP 4641201 A22025-10-29506Q9Y6K5Espacenet
JP 2025519096 A2025-06-2487Q9Y6K5Espacenet
JP 2025517969 A2025-06-12506Q9Y6K5Espacenet
JP 2025062604 A2025-04-14141Q9Y6K5Espacenet
US 11446398 B22022-09-20141Q9Y6K5Espacenet
JP 2022524081 A2022-04-27103112Q9Y6K5Espacenet
KR 1020210130270 A2021-10-2913Q9Y6K5Espacenet
JP 2021167336 A2021-10-2113Q9Y6K5Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,763

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleOAS3 papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award62025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center52025
P30CA008748Cancer Center Support Grant42025
P30CA091842Cancer Center Support Grant42025
P51OD010425Washington National Primate Research Center42025
P51OD011133The Southwest National Primate Research Center42025
U19AI135972SARS-CoV adaptations through a Systems Biology Lens (SYBIL)42025
U54CA1186381/3 Morehouse School of Medicine/Tuskegee University/University of Alabama at Birmingham O'Neal Comprehensive Cancer Center Partnership42025
U54GM104938Oklahoma Shared Clinical and Translational Resources42025
UL1TR002345Washington University Institute of Clinical and Translational Sciences42025

1 to 10 of 1,763Source NIH's project files

See all 1,763 nih grants

Papers2,054

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Advances in Cytosolic dsRNA Sensing of Viral Infections.Immunol Cell Biol202642802076PubTator, text miningPubMed
Integrated multi-omics analysis reveals shared IFN-γ-associated monocyte signatures in primary Sjögren's syndrome and Alzheimer's disease.Front Immunol202642780532PubTator, text miningPubMed
Transcriptomic characteristics of plasma from Chinese ethnic minority patients with major depressive disorder.Transl Psychiatry202642706240PubTator, text miningPubMed
Hypomethylation of the Human OAS2 Gene in Blood Cells as a Potential Biomarker for Rheumatoid Arthritis: Findings from an Iranian Case-control Study.Arch Iran Med202642604416PubTator, text miningPubMed
Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.Medicine (Baltimore)202642601724PubTator, text miningPubMed
Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants.PLoS Pathog202642497219PubTator, text miningPubMed
Stage-specific disruption of erythropoiesis leads to anemia in newly diagnosed multiple myeloma patients.Front Cell Dev Biol202642358738PubTator, text miningPubMed
Proteomics-based characterization of apigenin-mediated anti-inflammatory effects in TNF-α-stimulated ARPE-19 cells.Int Immunopharmacol202642322860PubTator, text miningPubMed
Genetic variations on influenza virus infection outcomes in Moroccan patients.Iran J Microbiol202642306510PubTator, text miningPubMed
Parimifasor elicits broad-spectrum antitumor effects by suppressing the expression of oncogenic genes.Transl Cancer Res202642305505PubTator, text miningPubMed

1 to 10 of 2,054

See all 2,054 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4940

GET https://conductscience.org/api/genes/v1/4940/patents?page=2