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Gene · 498

ATP5F1A: ATP synthase F1 subunit alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATP5F1A: ATP synthase F1 subunit alpha. Genes, record 498. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/498

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Gene

Symbol
ATP5F1A
HGNC
Name
ATP synthase F1 subunit alpha
HGNC
NCBI Gene ID
498
NCBI Gene
HGNC ID
HGNC:823
HGNC
Ensembl
ENSG00000152234
NCBI Gene
Aliases
ATP5A, ATP5A1, ATP5AL2, ATPM, COXPD22, HEL-S-123m, MC5DN4, MC5DN4A, MC5DN4B, MOM2, OMR, ORM, hATP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25705ATP synthase F(1) complex subunit alpha, mitochondrial5539Ensembl, GeneID, HGNC

Source UniProt

Patents82

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193147P25705Espacenet
JP 2025517970 A2025-06-123147P25705Espacenet
JP 2025062604 A2025-04-147027P25705Espacenet
JP 2025062604 A2025-04-147028P25705Espacenet
JP 2024123008 A2024-09-104943P25705Espacenet
JP 2024123008 A2024-09-104944P25705Espacenet
US 11898154 B22024-02-1366P25705Espacenet
US 11860162 B22024-01-021509P25705Espacenet
US 11694765 B22023-07-04100P25705Espacenet
US 11694765 B22023-07-04102P25705Espacenet

1 to 10 of 82

See all 82 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,107

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATP5F1A papersNewest fiscal year
P30CA008748Cancer Center Support Grant52025
P40OD010440Caenorhabditis Genetics Center52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control42025
UL1TR001863Yale Clinical and Translational Science Award42025
P01CA092584Structural Cell Biology of DNA Repair Machines32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA076292Moffitt Cancer Center Support Grant32025
R01NS095892IMPACTING MITOCHONDRIAL FUNCTION THROUGH ALTERED PROTEASE ACTIVITY32025
P30CA013696Cancer Center Support Grant22025
P30CA014195Cancer Center Support Grant (CCSG)22025

1 to 10 of 1,107Source NIH's project files

See all 1,107 nih grants

Papers1,557

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and evaluation of candidate sperm proteins associated with cryopreservation-induced changes in semen quality in Thai native roosters.Poult Sci202642785075PubTator, text miningPubMed
Ambrisentan rescues doxorubicin-induced cardiac apoptosis and mitochondrial bioenergetic dysfunction: Mechanistic insights into p53 and mTOR signaling.Biochem Pharmacol202642727655PubTator, text miningPubMed
The complete mitochondrial genome of Hemiboea subcapitata (Gesneriaceae) and comparative analysis across Lamiales.Front Plant Sci202642656881PubTator, text miningPubMed
Somatostatin expression is associated with mitochondrial-related gene expression in a brain region-specific manner: Evidence from human transcriptomic analysis.Behav Brain Res202642617977PubTator, text miningPubMed
Biological characteristics of ATP5A1 and its pathogenic mechanisms in human diseases: advances in clinical translation.Front Cell Dev Biol202642540428PubTator, text miningPubMed
Stage-associated immunoproteomic profiling of serum autoantibody-captured retinal antigens in age-related macular degeneration.Front Immunol202642488638PubTator, text miningPubMed
Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity.Front Tuberc202642368172PubTator, text miningPubMed
FABP5 confers resistance to drug-induced ROS toxicity in cervical cancer cell lines by suppressing the PPARγ/CPT1A signaling pathway.Discov Oncol202642184092PubTator, text miningPubMed
Hypoxia-driven microRNA-27b underlies pathologic cardiac endoreplication in heart disease.Signal Transduct Target Ther202642135278PubTator, text miningPubMed
Circle-mediated HGT shapes the multichromosomal mitochondrial genome of the endoparasitic plant Mitrastemon yamamotoi.Plant J202642012907PubTator, text miningPubMed

1 to 10 of 1,557

See all 1,557 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/498

GET https://conductscience.org/api/genes/v1/498/patents?page=2