Gene · 498
ATP5F1A: ATP synthase F1 subunit alpha
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATP5F1A: ATP synthase F1 subunit alpha. Genes, record 498. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/498
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P25705 | ATP synthase F(1) complex subunit alpha, mitochondrial | 553 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 3147 | P25705 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3147 | P25705 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7027 | P25705 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7028 | P25705 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 4943 | P25705 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 4944 | P25705 | Espacenet |
| US 11898154 B2 | 2024-02-13 | 66 | P25705 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1509 | P25705 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 100 | P25705 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 102 | P25705 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,107
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATP5F1A papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
| R01NS095892 | IMPACTING MITOCHONDRIAL FUNCTION THROUGH ALTERED PROTEASE ACTIVITY | 3 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 2 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
1 to 10 of 1,107Source NIH's project files
See all 1,107 nih grantsPapers1,557
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification and evaluation of candidate sperm proteins associated with cryopreservation-induced changes in semen quality in Thai native roosters. | Poult Sci | 2026 | 42785075 | PubTator, text mining | PubMed |
| Ambrisentan rescues doxorubicin-induced cardiac apoptosis and mitochondrial bioenergetic dysfunction: Mechanistic insights into p53 and mTOR signaling. | Biochem Pharmacol | 2026 | 42727655 | PubTator, text mining | PubMed |
| The complete mitochondrial genome of Hemiboea subcapitata (Gesneriaceae) and comparative analysis across Lamiales. | Front Plant Sci | 2026 | 42656881 | PubTator, text mining | PubMed |
| Somatostatin expression is associated with mitochondrial-related gene expression in a brain region-specific manner: Evidence from human transcriptomic analysis. | Behav Brain Res | 2026 | 42617977 | PubTator, text mining | PubMed |
| Biological characteristics of ATP5A1 and its pathogenic mechanisms in human diseases: advances in clinical translation. | Front Cell Dev Biol | 2026 | 42540428 | PubTator, text mining | PubMed |
| Stage-associated immunoproteomic profiling of serum autoantibody-captured retinal antigens in age-related macular degeneration. | Front Immunol | 2026 | 42488638 | PubTator, text mining | PubMed |
| Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity. | Front Tuberc | 2026 | 42368172 | PubTator, text mining | PubMed |
| FABP5 confers resistance to drug-induced ROS toxicity in cervical cancer cell lines by suppressing the PPARγ/CPT1A signaling pathway. | Discov Oncol | 2026 | 42184092 | PubTator, text mining | PubMed |
| Hypoxia-driven microRNA-27b underlies pathologic cardiac endoreplication in heart disease. | Signal Transduct Target Ther | 2026 | 42135278 | PubTator, text mining | PubMed |
| Circle-mediated HGT shapes the multichromosomal mitochondrial genome of the endoparasitic plant Mitrastemon yamamotoi. | Plant J | 2026 | 42012907 | PubTator, text mining | PubMed |
1 to 10 of 1,557
See all 1,557 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/498
GET https://conductscience.org/api/genes/v1/498/patents?page=2