Gene · 4986
Papers4,507
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
181 to 200 of 4,507
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Navacaprant, a Novel and Highly Selective Kappa Opioid Receptor Antagonist, in Adults With Major Depressive Disorder: A Randomized, Double-Blind Phase 2 Clinical Trial. | J Clin Psychopharmacol | 2025 | 40199329 | PubTator, text mining | PubMed |
| A human iPSC-derived midbrain neural stem cell model of prenatal opioid exposure and withdrawal: A proof of concept study. | PLoS One | 2025 | 40168407 | PubTator, text mining | PubMed |
| Real-world use of difelikefalin in hemodialysis patients at a large dialysis organization in the United States: a retrospective database study. | BMC Nephrol | 2025 | 40148786 | PubTator, text mining | PubMed |
| Morphine-Induced Antinociception Is Potentiated and Dopamine Elevations Are Inhibited by the Biased Kappa Opioid Receptor Agonist Triazole 1.1. | ACS Chem Neurosci | 2025 | 40129263 | PubTator, text mining | PubMed |
| The Dynorphin/-Opioid Receptor System at the Interface of Hyperalgesia/Hyperkatifeia and Addiction. | Curr Addict Rep | 2025 | 40124896 | PubTator, text mining | PubMed |
| Can dextromethorphan-bupropion reduce mental pain in depressed individuals? A generating hypothesis overview perspective. | Ann Gen Psychiatry | 2025 | 40098206 | PubTator, text mining | PubMed |
| Xylazine as an emerging new psychoactive substance; focuses on both 5-HT7 and κ-opioid receptors' molecular interactions and isosteric replacement. | Arch Pharm (Weinheim) | 2025 | 40091602 | PubTator, text mining | PubMed |
| Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities. | Eur J Med Chem | 2025 | 40068406 | PubTator, text mining | PubMed |
| Current Evidence for the Role of Rapid-Acting Antidepressants in Bipolar Depression: A Perspective and Plan for Action. | Biol Psychiatry | 2025 | 40064389 | PubTator, text mining | PubMed |
| Dezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry. | Front Neurosci | 2025 | 40040846 | PubTator, text mining | PubMed |
| Successful Use of Difelikefalin in Severe Chronic Kidney Disease-Associated Pruritus in a Patient With Complex Etiological Contributors: A Case Report. | Case Rep Nephrol | 2025 | 40040639 | PubTator, text mining | PubMed |
| Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice. | bioRxiv | 2025 | 40027836 | PubTator, text mining | PubMed |
| [Pharmacological, pharmacokinetic and clinical profiles of Difelikefalin (KORSUVA® IV Injection Syringe for Dialysis), a peripheral kappa opioid receptor agonist]. | Nihon Yakurigaku Zasshi | 2025 | 40024699 | PubTator, text mining | PubMed |
| A New Trick of Old Dogs: Can Kappa Opioid Receptor Antagonist Properties of Antidepressants Assist in Treating Treatment-Resistant Depression (TRD)? | Pharmaceuticals (Basel) | 2025 | 40006022 | PubTator, text mining | PubMed |
| A combined in silico approach to design peptide ligands with increased receptor-subtype selectivity. | J Mol Biol | 2025 | 39954776 | PubTator, text mining | PubMed |
| Comparison of effect and mechanism between nalfurafine hydrochloride and narrow-band ultraviolet B phototherapy in the treatment of pruritus in hemodialysis patients. | Ann Med | 2025 | 39946202 | PubTator, text mining | PubMed |
| Effects of Biased Analogues of the Kappa Opioid Receptor Agonist, U50,488, in Preclinical Models of Pain and Side Effects. | Molecules | 2025 | 39942708 | PubTator, text mining | PubMed |
| Unifying principles for the design and evaluation of natural product-inspired compound collections. | Chem Sci | 2025 | 39906386 | PubTator, text mining | PubMed |
| Novel chimeric peptides of endomorphin-2 and the active fragments of ghrelin exhibit blood-brain barrier permeability and central antinociceptive effects with reduced opioid-related side effects. | Neuropharmacology | 2025 | 39904410 | PubTator, text mining | PubMed |
| A review of kappa opioid receptor antagonists and their clinical trial landscape. | Eur J Med Chem | 2025 | 39893986 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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