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Gene · 501

ALDH7A1: aldehyde dehydrogenase 7 family member A1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ALDH7A1: aldehyde dehydrogenase 7 family member A1. Genes, record 501. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/501

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Gene

Symbol
ALDH7A1
HGNC
Name
aldehyde dehydrogenase 7 family member A1
HGNC
NCBI Gene ID
501
NCBI Gene
HGNC ID
HGNC:877
HGNC
Ensembl
ENSG00000164904
NCBI Gene
Aliases
ATQ1, EPD, EPEO4, PDE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P49419Alpha-aminoadipic semialdehyde dehydrogenase53920Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437045P49419Espacenet
EP 4650780 A22025-11-1912137P49419Espacenet
EP 4641202 A22025-10-296119P49419Espacenet
JP 2025111747 A2025-07-30145P49419Espacenet
JP 2025517970 A2025-06-1212137P49419Espacenet
JP 2025062604 A2025-04-143931P49419Espacenet
KR 1020250017231 A2025-02-046119P49419Espacenet
US 11892452 B22024-02-06135P49419Espacenet
US 11446398 B22022-09-203931P49419Espacenet
JP 2022092366 A2022-06-22696P49419Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,306

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleALDH7A1 papersNewest fiscal year
P20GM109025Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - Resubmission72025
R01DK073368Mechanisms of Compartmentalized cAMP Signaling62025
P30CA016672Cancer Center Support Grant52025
R01EY010843Regulation of Retinal cGMP-Phosphodiesterases52025
R01GM065546Substrate Channeling and Communication in Proline Metabolic Enzymes52025
T32HL007227Pathophysiology of Myocardial Disease52025
P30CA056036Translational Research in Cancer42025
P30DK056350Nutrition Obesity Research Center (NORC)42025
P30ES013508Center of Excellence in Environmental Toxicology42025
P51OD011132Emory National Primate Research Center42025

1 to 10 of 2,306Source NIH's project files

See all 2,306 nih grants

Papers3,847

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Novel Phosphodiesterase‑2 Inhibitors Discovered via Structure-Based Virtual Screening Targeting the Allosteric GAF‑B Domain.ACS Med Chem Lett202642741649PubTator, text miningPubMed
A multimodal adjoint-state formulation of Quantitative Photoacoustic Tomography with external acoustic sources.Photoacoustics202642724679PubTator, text miningPubMed
SMN deficiency causes cardiac adrenergic insensitivity via activation of the cAMP-PKA pathway.Neurobiol Dis202642648444PubTator, text miningPubMed
Diorcinol L, a natural pentenyl diphenyl ether isolated from Aspergillus sp. MA6037, exhibits cytotoxic activity by inhibiting KIF11.Arch Microbiol202642611269PubTator, text miningPubMed
FMEnets: Flow, material, and energy networks for non-ideal plug flow reactor design.Chem Eng Sci202642578006PubTator, text miningPubMed
AKAP12 as a signal-compartmentalizing Hub across diseases: Context-dependent functions and translational potential.Cell Signal202642571827PubTator, text miningPubMed
A geometric-surface PDE model for cell-nucleus translocation through confinement.PLoS Comput Biol202642531340PubTator, text miningPubMed
Pyridoxine-dependent and other pyridoxine-responsive epilepsies-insights into phenotype overlapping and the long-term outcome in a cohort of 21 children.Front Neurol202642516410PubTator, text miningPubMed
Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin.Cancer Biol Ther202642474358PubTator, text miningPubMed
Cerebral Energy Crisis in the Subacute Phase of Aneurysmal Subarachnoid Hemorrhage: A 31P-MRS Pilot Study on Cerebral Vasospasm and Delayed Cerebral Ischemia.Neurocrit Care202642449089PubTator, text miningPubMed

1 to 10 of 3,847

See all 3,847 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/501

GET https://conductscience.org/api/genes/v1/501/patents?page=2