ConductScience.org, home

Library / Genes

OXTR: oxytocin receptor

1 protein, 38 patents, 10 drugs, 289 trials, 2,429 NIH grants and 4,673 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolOXTRHGNC
Nameoxytocin receptorHGNC
NCBI Gene ID5021NCBI Gene
HGNC IDHGNC:8529HGNC
EnsemblENSG00000180914NCBI Gene
AliasesOT-R, OTRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P30559Oxytocin receptor3893Ensembl, GeneID, HGNCUniProt

Patents 38

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456827P30559Espacenet
JP 2025529142 A2025-09-043311P30559Espacenet
US 12371689 B22025-07-293311P30559Espacenet
US 11446398 B22022-09-2060762P30559Espacenet
JP 2022127080 A2022-08-311P30559Espacenet
US 11400116 B22022-08-027326P30559Espacenet
JP 2022099043 A2022-07-041P30559Espacenet
JP 2022524081 A2022-04-27163733P30559Espacenet
US 11307208 B22022-04-197P30559Espacenet
US 11078247 B22021-08-038043P30559Espacenet

Drugs 10

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATOSIBANCHEMBL382301Oxytocin receptor antagonistANTAGONISTChEMBL
ATOSIBAN ACETATECHEMBL5315050Oxytocin receptor antagonistANTAGONISTChEMBL
BARUSIBANCHEMBL2218898Oxytocin receptor antagonistANTAGONISTChEMBL
CARBETOCINCHEMBL3301668Oxytocin receptor agonistAGONISTChEMBL
EPELSIBANCHEMBL2037511Oxytocin receptor antagonistANTAGONISTChEMBL
FE 202767CHEMBL3545167Oxytocin receptor agonistAGONISTChEMBL
NOLASIBANCHEMBL1254025Oxytocin receptor antagonistANTAGONISTChEMBL
OXYTOCINCHEMBL395429Oxytocin receptor agonistAGONISTChEMBL
RELCOVAPTANCHEMBL419667Oxytocin receptor antagonistANTAGONISTChEMBL
RETOSIBANCHEMBL429736Oxytocin receptor antagonistANTAGONISTChEMBL

Trials 289

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07551882OXYTOCINPHASE2ClinicalTrials.gov
NCT07436286OXYTOCINClinicalTrials.gov
NCT07430228OXYTOCINPHASE2ClinicalTrials.gov
NCT07409753OXYTOCINPHASE2ClinicalTrials.gov
NCT07390864CARBETOCINClinicalTrials.gov
NCT07187544CARBETOCINClinicalTrials.gov
NCT07162584OXYTOCINClinicalTrials.gov
NCT07093060ATOSIBANEARLY_PHASE1ClinicalTrials.gov
NCT07093060OXYTOCINEARLY_PHASE1ClinicalTrials.gov
NCT07053774OXYTOCINPHASE2ClinicalTrials.gov

NIH grants 2429

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P51OD011132Emory National Primate Research Center552,025NIH's project files
P51OD011107California National Primate Research Center162,025NIH's project files
P30AG028740University of Florida Older Americans Independence Center (OAIC)132,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition112,025NIH's project files
R01HD098117Mechanisms of maternal brain changes with birth interventions102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
P30CA086862Cancer Center Support Grant92,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)82,025NIH's project files
T32NS096050Training In Systems And Integrative Biology Neuroscience82,025NIH's project files
R01MH113007The Integrated Role of Vasopressin and Oxytocin Receptors in the Modulation of BNST Activity and Fear Processing62,025NIH's project files

Papers 4673

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827426PubTator, text miningPubMed
42812628PubTator, text miningPubMed
42802704PubTator, text miningPubMed
42802640PubTator, text miningPubMed
42776672PubTator, text miningPubMed
42762647PubTator, text miningPubMed
42753417PubTator, text miningPubMed
42725451PubTator, text miningPubMed
42716459PubTator, text miningPubMed
42692757PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license