Gene · 5048
PAFAH1B1: platelet activating factor acetylhydrolase 1b regulatory subunit 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PAFAH1B1: platelet activating factor acetylhydrolase 1b regulatory subunit 1. Genes, record 5048. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5048
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | 410 | 21 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58135 | P43034 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12007 | P43034 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 12007 | P43034 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32842 | P43034 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32842 | P43034 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 644 | P43034 | Espacenet |
| JP 2024009871 A | 2024-01-23 | 80 | P43034 | Espacenet |
| JP 2023064789 A | 2023-05-12 | 89 | P43034 | Espacenet |
| KR 1020230064910 A | 2023-05-11 | 1 | P43034 | Espacenet |
| WO 2023074712 A | 2023-05-04 | 35 | P43034 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,317
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PAFAH1B1 papers | Newest fiscal year |
|---|---|---|---|
| R01NS032457 | Cell Identity Determination in Human Brain: Somatic Mutation and Cell Lineage | 11 | 2025 |
| R01NS058721 | ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders | 9 | 2025 |
| R35GM136414 | The Mechanism and Regulation of the Dynein Transport Machinery | 6 | 2025 |
| R35GM139483 | Regulation of Dynein-Mediated Transport | 6 | 2025 |
| R35GM141825 | Mechanisms of microtubule-based transport | 6 | 2025 |
| R37NS035129 | Human Epilepsy Genetics - Mosaic Mutations in Focal Epilepsy | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01GM098469 | Molecular Mechanism of the Cytoplasmic Dynein-Dynactin Motor Complex | 4 | 2025 |
| R35GM124889 | Coordination of molecular motor activity in intracellular transport and assembly of cytoskeletal archit | 4 | 2025 |
| R35GM126950 | Molecular Mechanisms of Axonal Transport and Organelle Dynamics | 4 | 2025 |
1 to 10 of 1,317Source NIH's project files
See all 1,317 nih grantsPapers1,956
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genotype-phenotypic correlation in a Chinese patient with isolated lissencephaly sequence caused by 17p13.3p13.2 chromosomal microdeletion: a 6-year follow-up study. | Front Genet | 2026 | 42775388 | PubTator, text mining | PubMed |
| USP6-FISH Negative Nodular Fasciitis: Benign Impostor of the Orbit. | Ophthalmic Plast Reconstr Surg | 2026 | 42727019 | PubTator, text mining | PubMed |
| [A case of bilateral open-lip schizencephaly with West syndrome due to variant of PAFAH1B1 gene and literature review]. | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | 2026 | 42711133 | PubTator, text mining | PubMed |
| Genotype-Driven MRI Re-evaluation Reveals Subtle PAFAH1B1-Related Lissencephaly. | J Child Neurol | 2026 | 42658896 | PubTator, text mining | PubMed |
| Corpus Callosotomy in LIS1 Lissencephaly: Postoperative Ketogenic Diet-Related Metabolic Derangements and Feeding Intolerance. | Cureus | 2026 | 42453837 | PubTator, text mining | PubMed |
| Deep learning-based identification of causative genes in lissencephaly using 3D-MRI volumetric datasets. | Neuroimage Rep | 2026 | 42381865 | PubTator, text mining | PubMed |
| Bronchoalveolar lavage microbiota signatures and stage-associated alterations in early-stage and advanced-stage non-small cell lung cancer: a pilot study. | J Transl Med | 2026 | 42321844 | PubTator, text mining | PubMed |
| The P3018S disease variant reveals how dynein's trailing motor sets ensemble velocity. | bioRxiv | 2026 | 42239374 | PubTator, text mining | PubMed |
| Structural and ensemble-based mechanistic insights into cytoplasmic dynein-1. | Front Mol Biosci | 2026 | 42181769 | PubTator, text mining | PubMed |
| Gene-specific long-term course, neurodevelopmental outcome and quality of life in patients with LIS1/PAFAH1B1-, DCX-, DYNC1H1-, TUBA1A- and TUBG1-related lissencephaly. | Orphanet J Rare Dis | 2026 | 42177523 | PubTator, text mining | PubMed |
1 to 10 of 1,956
See all 1,956 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5048
GET https://conductscience.org/api/genes/v1/5048/patents?page=2