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Gene · 50506

DUOX2: dual oxidase 2

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. DUOX2: dual oxidase 2. Genes, record 50506. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/50506

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
DUOX2
HGNC
Name
dual oxidase 2
HGNC
NCBI Gene ID
50506
NCBI Gene
HGNC ID
HGNC:13273
HGNC
Ensembl
ENSG00000140279
NCBI Gene
Aliases
LNOX2, NOXEF2, P138(TOX), P138-TOX, TDH6, THOX2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NRD8Dual oxidase 21,5480Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444306Q9NRD8Espacenet
EP 4650780 A22025-11-1918133Q9NRD8Espacenet
EP 4641201 A22025-10-2922519Q9NRD8Espacenet
JP 2025529142 A2025-09-041336Q9NRD8Espacenet
US 12371689 B22025-07-291336Q9NRD8Espacenet
JP 2025517969 A2025-06-1222519Q9NRD8Espacenet
JP 2025517970 A2025-06-1218133Q9NRD8Espacenet
US 11446398 B22022-09-2025703Q9NRD8Espacenet
US 11400116 B22022-08-023868Q9NRD8Espacenet
JP 2022524081 A2022-04-27128674Q9NRD8Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,925

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
ZIABC010677NADPH Oxidases as Novel Targets for Cancer Therapy152025
R01DK015070Thyroid Physiology Studies of Inherited Disorders122025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease112025
P30CA016672Cancer Center Support Grant92025
P30ES005605Environmental Health Sciences Research Center92025
ZIAAI000645Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies92025
ZIAAI000646Transgenic Animal Models Of Human Immune Defects92025
P30DK034854Integrated Epithelial and Muscosal Biology82025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital62025
ZIAAI000644Gene Therapy and Hematopoietic Stem Cell Research to Treat Inherited Primary Immune Deficiencies62025

1 to 10 of 1,925Source NIH's project files

See all 1,925 nih grants

Papers4,089

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42811155PubTator, text miningPubMed
42790002PubTator, text miningPubMed
42778017PubTator, text miningPubMed
42716511PubTator, text miningPubMed
42695417PubTator, text miningPubMed
42695285PubTator, text miningPubMed
42677613PubTator, text miningPubMed
42662067PubTator, text miningPubMed
42626711PubTator, text miningPubMed
42577684PubTator, text miningPubMed

1 to 10 of 4,089

See all 4,089 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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