ConductScience.org, home

Gene · 5052

PRDX1: peroxiredoxin 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PRDX1: peroxiredoxin 1. Genes, record 5052. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5052

On this page

Gene

Symbol
PRDX1
HGNC
Name
peroxiredoxin 1
HGNC
NCBI Gene ID
5052
NCBI Gene
HGNC ID
HGNC:9352
HGNC
Ensembl
ENSG00000117450
NCBI Gene
Aliases
MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q06830Peroxiredoxin-119920Ensembl, GeneID, HGNC

Source UniProt

Patents145

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-037Q06830Espacenet
EP 4650780 A22025-11-192113Q06830Espacenet
EP 4641202 A22025-10-294550Q06830Espacenet
WO 2025163153 A22025-08-0718Q06830Espacenet
JP 2025517970 A2025-06-122113Q06830Espacenet
KR 1020250017231 A2025-02-044550Q06830Espacenet
EP 4484957 A12025-01-0198Q06830Espacenet
US 12133879 B22024-11-057Q06830Espacenet
JP 2024112982 A2024-08-214425Q06830Espacenet
JP 2024112982 A2024-08-214426Q06830Espacenet

1 to 10 of 145

See all 145 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,121

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRDX1 papersNewest fiscal year
P30CA016056Roswell Park Cancer Center Support Grant142025
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant112025
P30CA012197Cancer Center Support Grant82025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant82025
P30CA046934University of Colorado Cancer Center Support Grant72025
P30ES006694Southwest Environmental Health Sciences Center72025
R01GM102187Chemical Tools for Probing Cysteine Sulfenation and Sulfination Redox Biology72025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant52025
P30CA047904Cancer Center Support Grant52025

1 to 10 of 2,121Source NIH's project files

See all 2,121 nih grants

Papers3,897

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
PRDX1 as a novel urinary biomarker for bladder cancer: Development of an integrated fiber optic sensing platform.Talanta202742349259PubTator, text miningPubMed
Research progress on the characterization, evolution and functions of molluscan peroxiredoxins.Dev Comp Immunol202642810604PubTator, text miningPubMed
Chemogenomic maps reveal a PRDX1-dependent iron-damage axis in the DNA damage response.Nat Chem Biol202642711491PubTator, text miningPubMed
PRDX1 facilitates USP7-dependent stabilization of SCD1 and promotes bladder cancer progression.Cell Signal202642705398PubTator, text miningPubMed
Identification of Immune Response-Related Proteomic Biomarkers in Moyamoya Disease Using Serum Olink Proteomics.J Proteome Res202642695863PubTator, text miningPubMed
Methodological approach to investigate peroxiredoxin 1 deacetylation by histone deacetylase 6.Methods Enzymol202642692764PubTator, text miningPubMed
Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species.Science202642691162PubTator, text miningPubMed
A peroxiredoxin 1-reactive oxygen species feedback loop modulates nuclear factor kappa B activity in osteoclastogenesis.Mol Biomed202642658444PubTator, text miningPubMed
Molecular Mechanisms Governing Vascular Function in Heart Failure.Arterioscler Thromb Vasc Biol202642619591PubTator, text miningPubMed
Placental PRDX2-VEGFA/ENG network rewiring links oxidative stress to angiogenic failure in preeclampsia: A multi-cohort transcriptomic study.Comput Biol Chem202642603350PubTator, text miningPubMed

1 to 10 of 3,897

See all 3,897 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5052

GET https://conductscience.org/api/genes/v1/5052/patents?page=2