Gene · 5055
SERPINB2: serpin family B member 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SERPINB2: serpin family B member 2. Genes, record 5055. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5055
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P05120 | Plasminogen activator inhibitor 2 | 415 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents145
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 239 | P05120 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3944 | P05120 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3521 | P05120 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 12078 | P05120 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 12079 | P05120 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7684 | P05120 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7684 | P05120 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3521 | P05120 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3944 | P05120 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 12078 | P05120 | Espacenet |
1 to 10 of 145
See all 145 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,602
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SERPINB2 papers | Newest fiscal year |
|---|---|---|---|
| P51OD011092 | Support for National Primate Research Center | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA134274 | UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT | 7 | 2025 |
| R01HL080414 | Phenotypic and biological features of mucus plugs in asthma | 5 | 2025 |
| U19AI077439 | Immune-driven Airway Epithelial Dysfunction in Muco-obstructive Asthma | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 4 | 2025 |
| R37AG013925 | Effect of Aging on Preadipocyte Differentiation | 4 | 2025 |
| U19AI070235 | Epithelial Genes in Allergic Inflammation | 4 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 4 | 2025 |
1 to 10 of 1,602Source NIH's project files
See all 1,602 nih grantsPapers3,233
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion. | Nature | 2026 | 42717081 | PubTator, text mining | PubMed |
| Combining co-expression analysis and machine learning to explore the diagnostic value of complement and coagulation cascade-related genes in asthma and the functional role of SERPINB2. | Brief Funct Genomics | 2026 | 42647769 | PubTator, text mining | PubMed |
| Allicin Attenuates Silica-Induced Pulmonary Fibrosis by Targeting the Serpinb2/NF-κB Pathway. | J Biochem Mol Toxicol | 2026 | 42438949 | PubTator, text mining | PubMed |
| Inhibition of inflammation and senescence with azole compound C7 enables expansion of hematopoietic stem and progenitor cells. | Stem Cells Transl Med | 2026 | 42387854 | PubTator, text mining | PubMed |
| Increased induced sputum ITGB5 expression was correlated with airway inflammation and lung function in asthma. | J Asthma | 2026 | 42370849 | PubTator, text mining | PubMed |
| Transcriptomic Profile of Genes Regulating Cellular Response to Extra- and Intracellular Stimuli in Porcine Ovarian Granulosa Cells During In Vitro Cultivation. | Int J Mol Sci | 2026 | 42353161 | PubTator, text mining | PubMed |
| Epithelial SERPINB2 Overexpression Contributes to Impaired Fibrinolysis in Chronic Rhinosinusitis With Nasal Polyps via tPA Downregulation. | Front Biosci (Landmark Ed) | 2026 | 42216541 | PubTator, text mining | PubMed |
| PTSD and complex PTSD differ significantly in plasma levels of IL2 and MMP9: patterns associated with traumatic brain injury. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42012659 | PubTator, text mining | PubMed |
| Author Correction: Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation. | Nat Commun | 2026 | 41997981 | PubTator, text mining | PubMed |
| Tumor-Specific Pro-Thrombotic Gene Expression in Head and Neck Squamous Cell Carcinoma: A Multi-Cohort Transcriptomic Analysis. | Cancers (Basel) | 2026 | 41976278 | PubTator, text mining | PubMed |
1 to 10 of 3,233
See all 3,233 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5055
GET https://conductscience.org/api/genes/v1/5055/patents?page=2