Gene · 50604
IL20: interleukin 20
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL20: interleukin 20. Genes, record 50604. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/50604
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NYY1 | Interleukin-20 | 176 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents292
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026086743 A | 2026-05-26 | 153 | Q9NYY1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8172 | Q9NYY1 | Espacenet |
| US 12473363 B2 | 2025-11-18 | 915 | Q9NYY1 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6998 | Q9NYY1 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6999 | Q9NYY1 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16750 | Q9NYY1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6720 | Q9NYY1 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6720 | Q9NYY1 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8172 | Q9NYY1 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 6998 | Q9NYY1 | Espacenet |
1 to 10 of 292
See all 292 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| FLETIKUMAB | CHEMBL3301580 | Interleukin-20 inhibitor | INHIBITOR |
Source ChEMBL
Trials6
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02097264 | FLETIKUMAB | PHASE2 | ClinicalTrials.gov | |
| NCT01636843 | FLETIKUMAB | PHASE2 | ClinicalTrials.gov | |
| NCT01636817 | FLETIKUMAB | PHASE2 | ClinicalTrials.gov | |
| NCT01282255 | FLETIKUMAB | PHASE2 | ClinicalTrials.gov | |
| NCT01261767 | FLETIKUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT00818064 | FLETIKUMAB | PHASE1 | ClinicalTrials.gov |
NIH grants1,024
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL20 papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 10 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 5 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| ZIAAI001065 | India International Center for Excellence in Research | 4 | 2025 |
| ZIAAR041159 | Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases | 4 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 3 | 2025 |
| T32AR007197 | Training Grant in Cell and Molecular Dermatology | 3 | 2025 |
| U19AI095227 | Viral and Host Determinants of Infant and Childhood Allergy and Asthma | 3 | 2025 |
1 to 10 of 1,024Source NIH's project files
See all 1,024 nih grantsPapers1,802
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Calpeptin and protein kinase C inhibition suppress exosome-associated inflammatory signaling and epidermal dysregulation in a 3-dimensional psoriatic skin model. | J Pharmacol Exp Ther | 2026 | 42731396 | PubTator, text mining | PubMed |
| The neuroimmune network in Alzheimer's and Parkinson's diseases: from mechanistic insights to biomarker-guided immunotherapies and clinical translation. | Inflammopharmacology | 2026 | 42627617 | PubTator, text mining | PubMed |
| Signal peptide-mediated endoplasmic reticulum targeting enhances antigen expression and secretion to improve mRNA vaccine efficacy. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 42550669 | PubTator, text mining | PubMed |
| Proteomic landscapes of post-COVID condition: biomarkers and translational pathways. | Front Immunol | 2026 | 42421959 | PubTator, text mining | PubMed |
| Microwave treatment of human papillomavirus-positive in vitro grown epithelial tissues results in a rapid stress-related transcriptional response and induction of innate immunity. | Int J Hyperthermia | 2026 | 42381515 | PubTator, text mining | PubMed |
| Dynamics of the Interleukin-10 Family of Cytokines in Chronic Otitis Media Patients upon 1,8-Cineol Treatment. | In Vivo | 2026 | 42379782 | PubTator, text mining | PubMed |
| Early-life proteomic and microbiome features signal obesity risk across 26 years of follow-up. | mSystems | 2026 | 42206849 | PubTator, text mining | PubMed |
| Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study. | J Clin Lab Anal | 2026 | 42104642 | PubTator, text mining | PubMed |
| DNA aptamers that inhibit binding to human interleukin-17A and interleukin-20. | RSC Adv | 2026 | 42017161 | PubTator, text mining | PubMed |
| Proliferation-associated protein 2G4 promotes keratinocyte proliferation and survival in psoriasis. | Br J Dermatol | 2026 | 42008715 | PubTator, text mining | PubMed |
1 to 10 of 1,802
See all 1,802 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/50604
GET https://conductscience.org/api/genes/v1/50604/patents?page=2