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Gene · 50604

IL20: interleukin 20

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IL20: interleukin 20. Genes, record 50604. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/50604

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Gene

Symbol
IL20
HGNC
Name
interleukin 20
HGNC
NCBI Gene ID
50604
NCBI Gene
HGNC ID
HGNC:6002
HGNC
Ensembl
ENSG00000162891
NCBI Gene
Aliases
IL-20, IL10D, ZCYTO10
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NYY1Interleukin-201761Ensembl, GeneID, HGNC

Source UniProt

Patents292

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086743 A2026-05-26153Q9NYY1Espacenet
EP 4650780 A22025-11-198172Q9NYY1Espacenet
US 12473363 B22025-11-18915Q9NYY1Espacenet
JP 2025147176 A2025-10-066998Q9NYY1Espacenet
JP 2025147176 A2025-10-066999Q9NYY1Espacenet
JP 2025147176 A2025-10-0616750Q9NYY1Espacenet
JP 2025529142 A2025-09-046720Q9NYY1Espacenet
US 12371689 B22025-07-296720Q9NYY1Espacenet
JP 2025517970 A2025-06-128172Q9NYY1Espacenet
JP 2025028160 A2025-02-286998Q9NYY1Espacenet

1 to 10 of 292

See all 292 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
FLETIKUMABCHEMBL3301580Interleukin-20 inhibitorINHIBITOR

Source ChEMBL

Trials6

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02097264FLETIKUMABPHASE2ClinicalTrials.gov
NCT01636843FLETIKUMABPHASE2ClinicalTrials.gov
NCT01636817FLETIKUMABPHASE2ClinicalTrials.gov
NCT01282255FLETIKUMABPHASE2ClinicalTrials.gov
NCT01261767FLETIKUMABPHASE1ClinicalTrials.gov
NCT00818064FLETIKUMABPHASE1ClinicalTrials.gov

NIH grants1,024

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL20 papersNewest fiscal year
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success102025
P30CA016059Massey Cancer Center - Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant62025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center52025
P30CA016087Cancer Center Support Grant42025
ZIAAI001065India International Center for Excellence in Research42025
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases42025
P30EY010572Ophthalmology Core Facility32025
T32AR007197Training Grant in Cell and Molecular Dermatology32025
U19AI095227Viral and Host Determinants of Infant and Childhood Allergy and Asthma32025

1 to 10 of 1,024Source NIH's project files

See all 1,024 nih grants

Papers1,802

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Calpeptin and protein kinase C inhibition suppress exosome-associated inflammatory signaling and epidermal dysregulation in a 3-dimensional psoriatic skin model.J Pharmacol Exp Ther202642731396PubTator, text miningPubMed
The neuroimmune network in Alzheimer's and Parkinson's diseases: from mechanistic insights to biomarker-guided immunotherapies and clinical translation.Inflammopharmacology202642627617PubTator, text miningPubMed
Signal peptide-mediated endoplasmic reticulum targeting enhances antigen expression and secretion to improve mRNA vaccine efficacy.Acta Biochim Biophys Sin (Shanghai)202642550669PubTator, text miningPubMed
Proteomic landscapes of post-COVID condition: biomarkers and translational pathways.Front Immunol202642421959PubTator, text miningPubMed
Microwave treatment of human papillomavirus-positive in vitro grown epithelial tissues results in a rapid stress-related transcriptional response and induction of innate immunity.Int J Hyperthermia202642381515PubTator, text miningPubMed
Dynamics of the Interleukin-10 Family of Cytokines in Chronic Otitis Media Patients upon 1,8-Cineol Treatment.In Vivo202642379782PubTator, text miningPubMed
Early-life proteomic and microbiome features signal obesity risk across 26 years of follow-up.mSystems202642206849PubTator, text miningPubMed
Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study.J Clin Lab Anal202642104642PubTator, text miningPubMed
DNA aptamers that inhibit binding to human interleukin-17A and interleukin-20.RSC Adv202642017161PubTator, text miningPubMed
Proliferation-associated protein 2G4 promotes keratinocyte proliferation and survival in psoriasis.Br J Dermatol202642008715PubTator, text miningPubMed

1 to 10 of 1,802

See all 1,802 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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