Gene · 5066
PAM: peptidylglycine alpha-amidating monooxygenase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PAM: peptidylglycine alpha-amidating monooxygenase. Genes, record 5066. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5066
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P19021 | Peptidyl-glycine alpha-amidating monooxygenase | 973 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents54
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026510789 A | 2026-04-10 | 1 | P19021 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 57293 | P19021 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 374 | P19021 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 12787 | P19021 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 2144 | P19021 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 14228 | P19021 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 9974 | P19021 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3333 | P19021 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7263 | P19021 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3333 | P19021 | Espacenet |
1 to 10 of 54
See all 54 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,033
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PAM papers | Newest fiscal year |
|---|---|---|---|
| R01DK031450 | Mechanistic Intermediates in Copper Oxygenases and Oxidases | 22 | 2025 |
| P30DK116074 | Stanford Diabetes Research Center | 6 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| R01DK062370 | Identifying Genes for Type 2 Diabetes: FUSION | 4 | 2025 |
| ZIAHG000024 | Genetic analysis of type II diabetes | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30DA018310 | Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling | 3 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 3 | 2025 |
| P30GM133894 | A Synchrotron Radiation Structural Biology Resource | 3 | 2025 |
| R01DK093757 | Genetic epidemiology of rare and regulatory variants for metabolic traits | 3 | 2025 |
1 to 10 of 1,033Source NIH's project files
See all 1,033 nih grantsPapers2,423
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Impaired peptide amidation and risk of incident dementia in the Malmoe preventive project cohort. | Alzheimers Res Ther | 2026 | 42811373 | PubTator, text mining | PubMed |
| Haplotype-resolved autotetraploid genome of Dioscorea nipponica provides insights into recent polyploidization, metabolic rewiring, and environmental adaptation. | Plant J | 2026 | 42804372 | PubTator, text mining | PubMed |
| Genetically supported targets and drug repurposing for sleep disorders: a Mendelian randomization systematic study. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42760376 | PubTator, text mining | PubMed |
| Evolution and Expression Divergence of Legume PAL Genes Suggest Associations with Drought Response and Root Nodule Development. | J Agric Food Chem | 2026 | 42715939 | PubTator, text mining | PubMed |
| Takotsubo syndrome diagnosis: the biomarker-based BioTAK score. | Eur Heart J | 2026 | 42670759 | PubTator, text mining | PubMed |
| Adrenomedullin system dysregulation predicts cardiogenic shock and mortality in acute coronary syndromes. | Eur Heart J | 2026 | 42668424 | PubTator, text mining | PubMed |
| Effects of Electrolyzed Functional Water Combined with Modified Atmosphere Storage on Postharvest Quality of Arrow Bamboo Shoots. | Foods | 2026 | 42650592 | PubTator, text mining | PubMed |
| Concentration-Dependent Effects of Salicylic Acid and Methyl Salicylate on Chlorophylls, Carotenoids, Fatty Acids, and Phenolic Compounds in the Green Microalga Planktochlorella nurekis. | Mar Drugs | 2026 | 42646483 | PubTator, text mining | PubMed |
| Genomes of Poaceae relatives reveal key metabolic innovations preceding the evolution of grasses. | Science | 2026 | 42623474 | PubTator, text mining | PubMed |
| Tri-frequency ultrasonication priming enhances germination, nutritional quality and techno-functional properties of tartary buckwheat. | Ultrason Sonochem | 2026 | 42604605 | PubTator, text mining | PubMed |
1 to 10 of 2,423
See all 2,423 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5066
GET https://conductscience.org/api/genes/v1/5066/patents?page=2