ConductScience.org, home

Gene · 5068

REG3A: regenerating family member 3 alpha

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. REG3A: regenerating family member 3 alpha. Genes, record 5068. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5068

On this page

Gene

Symbol
REG3A
HGNC
Name
regenerating family member 3 alpha
HGNC
NCBI Gene ID
5068
NCBI Gene
HGNC ID
HGNC:8601
HGNC
Ensembl
ENSG00000172016
NCBI Gene
Aliases
HIP, HIP/PAP, INGAP, PAP, PAP-H, PAP1, PBCGF, REG-III, REG3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q06141Regenerating islet-derived protein 3-alpha1754Ensembl, GeneID, HGNC

Source UniProt

Patents206

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026517378 A2026-05-294Q06141Espacenet
EP 4650780 A22025-11-194265Q06141Espacenet
EP 4641201 A22025-10-293826Q06141Espacenet
JP 2025147176 A2025-10-0611302Q06141Espacenet
JP 2025147176 A2025-10-0611303Q06141Espacenet
JP 2025147176 A2025-10-0611304Q06141Espacenet
JP 2025138725 A2025-09-252053Q06141Espacenet
JP 2025138725 A2025-09-252661Q06141Espacenet
JP 2025138725 A2025-09-252792Q06141Espacenet
JP 2025529142 A2025-09-047544Q06141Espacenet

1 to 10 of 206

See all 206 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,693

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleREG3A papersNewest fiscal year
P01CA039542Cellular and Molecular Studies of Bone Marrow Transplant332025
P30CA008748Cancer Center Support Grant112025
P30CA196521The Tisch Cancer Institute - Cancer Center Support Grant92025
P30CA016672Cancer Center Support Grant82025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies72025
R01DK070855Microbial Regulation of Retinol Transport and its Role in Intestinal Immunity72025
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research72025
P01CA018029Adult Leukemia Research Center52025
P30CA077598Cancer Center Support Grant52025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease52025

1 to 10 of 1,693Source NIH's project files

See all 1,693 nih grants

Papers2,978

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and validation of a robust inflammation-related three-gene signature for the diagnosis of neonatal necrotizing enterocolitis via machine learning integration.Pediatr Surg Int202642799867PubTator, text miningPubMed
Primary Neoplasms of the Seminal Vesicles: A Narrative Review of Carcinoma and the Rarer Non-Epithelial and Biphasic Tumours.Diagnostics (Basel)202642793728PubTator, text miningPubMed
Regenerating Islet-Derived 3α Is a Predictive Biomarker of Complicated Disease From Preclinical Through Established Crohn's Disease.Clin Gastroenterol Hepatol202642685961PubTator, text miningPubMed
Second-line and salvage therapies for steroid-refractory acute graft-versus-host disease: an integrated synthesis of current evidence and clinical sequencing.Curr Opin Hematol202642673530PubTator, text miningPubMed
Proteomics in the discovery of biomarkers of major complications after allogeneic hematopoietic cell transplantation.Curr Opin Hematol202642673525PubTator, text miningPubMed
An axon-intrinsic loop restricts nerve regeneration through axonal protein synthesis.Sci Adv202642647628PubTator, text miningPubMed
Human milk oligosaccharide (2'-FL) modifies the gut microbiome in children after bone marrow transplant.Blood202642622257PubTator, text miningPubMed
Revised porcine IgG subclass classification based on innate immune cell activation.Front Immunol202642602303PubTator, text miningPubMed
Association between gut epithelial barrier biomarkers and LDL-cholesterol in HIV-infected individuals.Medicine (Baltimore)202642601778PubTator, text miningPubMed
[The Impact of Nutritional Intervention on Complications and Prognosis of Hematopoietic Stem Cell Transplantation Patients].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544681PubTator, text miningPubMed

1 to 10 of 2,978

See all 2,978 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5068

GET https://conductscience.org/api/genes/v1/5068/patents?page=2