Gene · 5069
PAPPA: pappalysin 1
11 sourcesgene-search-2026-11-11-0.1.0
Cite this record
ConductScience Library. PAPPA: pappalysin 1. Genes, record 5069. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/5069
On this page
Gene
Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13219 | Pappalysin-1 | 1,627 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents57
Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026219836 A1 | 2026-10-22 | 57 | Q13219 | Espacenet |
| US 12606639 B2 | 2026-04-21 | 1 | Q13219 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 58988 | Q13219 | Espacenet |
| JP 2025539937 A | 2025-12-10 | 79 | Q13219 | Espacenet |
| WO 2025242652 A1 | 2025-11-27 | 1 | Q13219 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5868 | Q13219 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5590 | Q13219 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 9992 | Q13219 | Espacenet |
| EP 4619023 A1 | 2025-09-24 | 79 | Q13219 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7266 | Q13219 | Espacenet |
1 to 10 of 57
See all 57 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,176
NIH projects whose papers are about the gene, through NIH's grant-paper links.
| Project | Title | Its papers about the gene | Newest fiscal year |
|---|---|---|---|
| T32DK007352 | Diabetes and Metabolism | 8 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 8 | 2025 |
| K12HD000849 | Reproductive Scientist Development Program | 4 | 2025 |
| R37AG013925 | Effect of Aging on Preadipocyte Differentiation | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| P50HD103555 | Baylor College of Medicine Intellectual and Developmental Disabilities Research Center | 3 | 2025 |
| R01DK075787 | Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum | 3 | 2025 |
| R01HD055651 | Prenatal Genetic Diagnosis by Genomic Sequencing: A Prospective Evaluation | 3 | 2025 |
| R35GM126956 | Discovery and mechanisms of biosynthetic enzymes | 3 | 2025 |
1 to 10 of 1,176Source NIH's project files
See all 1,176 nih grantsPapers4,258
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| PMID | Found by | Source |
|---|---|---|
| 42801806 | PubTator, text mining | PubMed |
| 42796410 | PubTator, text mining | PubMed |
| 42794985 | PubTator, text mining | PubMed |
| 42793480 | PubTator, text mining | PubMed |
| 42766089 | PubTator, text mining | PubMed |
| 42759252 | PubTator, text mining | PubMed |
| 42739747 | PubTator, text mining | PubMed |
| 42732549 | PubTator, text mining | PubMed |
| 42732391 | PubTator, text mining | PubMed |
| 42725516 | PubTator, text mining | PubMed |
1 to 10 of 4,258
See all 4,258 papersSources 11
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNone stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GeneNone named. Public domain as US government information
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5069
GET https://conductscience.org/api/genes/v1/5069/patents?page=2