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Gene · 5087

PBX1: PBX homeobox 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PBX1: PBX homeobox 1. Genes, record 5087. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5087

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Gene

Symbol
PBX1
HGNC
Name
PBX homeobox 1
HGNC
NCBI Gene ID
5087
NCBI Gene
HGNC ID
HGNC:8632
HGNC
Ensembl
ENSG00000185630
NCBI Gene
Aliases
CAKUHED
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P40424Pre-B-cell leukemia transcription factor 14302Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16629P40424Espacenet
JP 2026004568 A2026-01-1458888P40424Espacenet
EP 4650780 A22025-11-1913373P40424Espacenet
EP 4640849 A22025-10-292323P40424Espacenet
EP 4641201 A22025-10-2915231P40424Espacenet
JP 2025147176 A2025-10-0615469P40424Espacenet
JP 2025519096 A2025-06-242323P40424Espacenet
JP 2025517969 A2025-06-1215231P40424Espacenet
JP 2025517970 A2025-06-1213373P40424Espacenet
JP 2025028160 A2025-02-2815469P40424Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,891

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePBX1 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)912025
P30CA008748Cancer Center Support Grant292025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement212025
U10CA180899Children's Oncology Group Statistics and Data Center202025
P30CA016672Cancer Center Support Grant172025
R01CA157644Central tolerance mechanisms in B-cell malignancies152025
R01AI045050Characterization of SLE-susceptibility loci on mouse chromosome 1132025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia122025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)102025
R01DE024745Pbx-Directed Control of Cellular Behaviors that Drive Midface Morphogenesis92025

1 to 10 of 1,891Source NIH's project files

See all 1,891 nih grants

Papers3,285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lactate-Mediated Lysine Lactylation in Renal Fibrosis: Current Progress and Challenges.FASEB J202642703165PubTator, text miningPubMed
Exploring the Impact of miR-10a, miR-141, miR-200a and miR-3658 on Cystinuria.Biomedicines202642652071PubTator, text miningPubMed
Cord Blood DNA Methylation and Large-for-Gestational-Age Birth: A Pilot Epigenome-Wide Study in the GROW Cohort.Epigenomes202642647200PubTator, text miningPubMed
Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging.Sci Adv202642627902PubTator, text miningPubMed
miRNA-mRNA Interaction Network Analysis in Alzheimer's Disease for Biomarker Discovery.J Mol Neurosci202642554796PubTator, text miningPubMed
Integrated Interactomics Reveals Novel Protein Associations: The FOXA1-PBX1 Complex as a Case Study.bioRxiv202642523200PubTator, text miningPubMed
The association study between MTOR and high myopia.Adv Ophthalmol Pract Res202642502695PubTator, text miningPubMed
Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT.Adv Sci (Weinh)202642474085PubTator, text miningPubMed
NTRK fusion in metastatic castration-resistant prostate cancer treated with entrectinib: a case report.J Med Case Rep202642469872PubTator, text miningPubMed
Accelerated Biological Aging Increases the Risk of Head and Neck Cancer: Insights From Genetic Instruments of Epigenetic Clocks.Mol Carcinog202642391445PubTator, text miningPubMed

1 to 10 of 3,285

See all 3,285 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5087

GET https://conductscience.org/api/genes/v1/5087/patents?page=2