Gene · 5093
PCBP1: poly(rC) binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PCBP1: poly(rC) binding protein 1. Genes, record 5093. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5093
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15365 | Poly(rC)-binding protein 1 | 356 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58361 | Q15365 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4353 | Q15365 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3896 | Q15365 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15473 | Q15365 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3896 | Q15365 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4353 | Q15365 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33051 | Q15365 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15473 | Q15365 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15473 | Q15365 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 33051 | Q15365 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,103
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PCBP1 papers | Newest fiscal year |
|---|---|---|---|
| R01CA154663 | TGFbeta-regulated epithelial-mesenchymal transition (EMT) | 20 | 2025 |
| ZIADK054510 | Identification of human genes of iron homeostasis | 18 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 5 | 2025 |
| ZIABC010419 | Molecular Mechanisms of TGF-beta Signaling Pathway | 5 | 2025 |
| U54DK110858 | Center for Iron & Heme Disorders at the University of Utah | 4 | 2025 |
| ZIAHD008814 | Mammalian iron-sulfur cluster biogenesis | 4 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 3 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,103Source NIH's project files
See all 1,103 nih grantsPapers1,671
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Promising reference genes for RT-qPCR normalization in breast tumors and normal adjacent tissues. | Mol Biol Rep | 2026 | 42801429 | PubTator, text mining | PubMed |
| De novo variants in the poly(rC)-binding protein gene PCBP1 cause a neurodevelopmental disorder. | Mol Psychiatry | 2026 | 42749777 | PubTator, text mining | PubMed |
| Corrigendum to "TBBPA induced hepatocyte ferroptosis by PCBP1-mediated ferritinophagy" [J Hazard Mater 494 (2025) 138515]. | J Hazard Mater | 2026 | 42692919 | PubTator, text mining | PubMed |
| PCBP1 Joins the Regulatory Network of the Endothelial-to-Hematopoietic Transition. | Exp Hematol | 2026 | 42603606 | PubTator, text mining | PubMed |
| TDP-43 drives ferroptosis evasion by modulating PCBP1/PCBP2 axis to promote lung adenocarcinoma growth. | Redox Biol | 2026 | 42585793 | PubTator, text mining | PubMed |
| The emerging role of ZDHHC9 in cancer: from protein palmitoylation to tumor progression and immune regulation. | Front Immunol | 2026 | 42528569 | PubTator, text mining | PubMed |
| Colorectal cancer-associated PCBP1 mutations disrupt protein stability in a dominant-negative manner. | J Biol Chem | 2026 | 42520935 | PubTator, text mining | PubMed |
| "Lights, camera, (ac)tion!": Damage-induced PCBP1 deacetylation releases PARP1 to engage DNA double-strand breaks. | Mol Cell | 2026 | 42462698 | PubTator, text mining | PubMed |
| APE1 binds and processes abasic sites present in i-motif DNA and cooperates with PCBP1 in maintenance of telomeric stability. | Nucleic Acids Res | 2026 | 42417194 | PubTator, text mining | PubMed |
| A P-body-related risk score predicts prognosis and immune microenvironment in lung adenocarcinoma. | Transl Cancer Res | 2026 | 42305460 | PubTator, text mining | PubMed |
1 to 10 of 1,671
See all 1,671 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5093
GET https://conductscience.org/api/genes/v1/5093/patents?page=2