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Gene · 5094

PCBP2: poly(rC) binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PCBP2: poly(rC) binding protein 2. Genes, record 5094. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5094

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Gene

Symbol
PCBP2
HGNC
Name
poly(rC) binding protein 2
HGNC
NCBI Gene ID
5094
NCBI Gene
HGNC ID
HGNC:8648
HGNC
Ensembl
ENSG00000197111
NCBI Gene
Aliases
HNRNPE2, HNRPE2, hnRNP-E2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15366Poly(rC)-binding protein 23655Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458363Q15366Espacenet
EP 4650780 A22025-11-1913548Q15366Espacenet
JP 2025147176 A2025-10-0615474Q15366Espacenet
JP 2025517970 A2025-06-1213548Q15366Espacenet
JP 2025028160 A2025-02-2815474Q15366Espacenet
KR 1020250010750 A2025-01-2115474Q15366Espacenet
JP 2024109657 A2024-08-1415313Q15366Espacenet
US 11446398 B22022-09-2064697Q15366Espacenet
JP 2022524081 A2022-04-27167668Q15366Espacenet
JP 2021536249 A2021-12-2715667Q15366Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,181

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePCBP2 papersNewest fiscal year
ZIADK054510Identification of human genes of iron homeostasis122025
P30CA062203Cancer Center Support Grant72025
P30CA016058Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025
P20GM103427Nebraska Research Network in Functional Genomics32025
P30CA043703Case Comprehensive Cancer Center Support Grant32025
P30CA076292Moffitt Cancer Center Support Grant32025
R01AR049737Epidermal Signaling Regulators32025

1 to 10 of 1,181Source NIH's project files

See all 1,181 nih grants

Papers1,668

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities.MedComm (2020)202642769510PubTator, text miningPubMed
PCBP2 facilitates miR-93-5p-mediated repression of GDF11 in HCC cell lines.Mol Ther Nucleic Acids202642732236PubTator, text miningPubMed
RETRACTION: PCBP2 Promotes the Development of Glioma by Regulating FHL3/TGF-β/Smad Signaling Pathway.J Cell Physiol202642627232PubTator, text miningPubMed
N6-methyladenosine-modified circLPAR3 drives docetaxel resistance in prostate cancer by suppressing ferroptosis through the PCBP2/CHAC1 axis.Genes Dis202642621305PubTator, text miningPubMed
TDP-43 drives ferroptosis evasion by modulating PCBP1/PCBP2 axis to promote lung adenocarcinoma growth.Redox Biol202642585793PubTator, text miningPubMed
The lncRNA Gm16685 / MITA1 modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling.bioRxiv202642465384PubTator, text miningPubMed
EGFR mimotope alleviates renal fibrosis by promoting EGFR/RPL6/PCBP2 ternary complex formation.NPJ Vaccines202642399607PubTator, text miningPubMed
A novel role of circCPSF6 regulating antiviral innate immunity via miR-665 and PCBP2-IPS-1 axis in IAV infection.Mol Ther Nucleic Acids202642367247PubTator, text miningPubMed
Radiation-Induced Tumor-Intrinsic LTβR N-Glycosylation Suppresses Pyroptosis Through TRIM28-Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance.Adv Sci (Weinh)202642325190PubTator, text miningPubMed
A P-body-related risk score predicts prognosis and immune microenvironment in lung adenocarcinoma.Transl Cancer Res202642305460PubTator, text miningPubMed

1 to 10 of 1,668

See all 1,668 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5094

GET https://conductscience.org/api/genes/v1/5094/patents?page=2