Gene · 51
ACOX1: acyl-CoA oxidase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACOX1: acyl-CoA oxidase 1. Genes, record 51. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15067 | Peroxisomal acyl-coenzyme A oxidase 1 | 660 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 343 | Q15067 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 36273 | Q15067 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4088 | Q15067 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4088 | Q15067 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 1882 | Q15067 | Espacenet |
| JP 2023521663 A | 2023-05-25 | 342 | Q15067 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 1882 | Q15067 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 104853 | Q15067 | Espacenet |
| JP 2021530985 A | 2021-11-18 | 450 | Q15067 | Espacenet |
| WO 2021202604 A1 | 2021-10-07 | 343 | Q15067 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,171
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACOX1 papers | Newest fiscal year |
|---|---|---|---|
| ZIABC005562 | Xenobiotic receptors | 10 | 2025 |
| ZIABC005708 | Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers | 9 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 6 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30DK020579 | Diabetes Research Center | 3 | 2025 |
1 to 10 of 1,171Source NIH's project files
See all 1,171 nih grantsPapers2,671
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrating in vivo metabolism, pharmacokinetics, and dual-indicator scoring for PK-marker selection of Celosiae Semen saponins. | J Pharm Biomed Anal | 2027 | 42815117 | PubTator, text mining | PubMed |
| Multi-omic profiling and pathways related to changes in liver histology after Roux-en-Y gastric bypass: a longitudinal study. | EBioMedicine | 2026 | 42810054 | PubTator, text mining | PubMed |
| ACOX1 downregulation contributes to macrophage M1 polarization and neutrophilic airway inflammation in asthma. | Int Immunopharmacol | 2026 | 42772039 | PubTator, text mining | PubMed |
| FSCN1 Modulates Fatty Acid Metabolism and the Coordinated Activation of AKT/mTOR and p38 MAPK Pathways in Colorectal Cancer Cells. | Oncol Res | 2026 | 42769853 | PubTator, text mining | PubMed |
| Impaired Photorespiratory Metabolism Underlies the Decline in CO2 Assimilation Induced by Alternative Oxidase Inhibition in Rumex K-1 Leaves. | Plants (Basel) | 2026 | 42739504 | PubTator, text mining | PubMed |
| Aryl hydrocarbon receptor as a molecular mediator in the induction of human aldehyde oxidase gene expression. | J Pharmacol Exp Ther | 2026 | 42664535 | PubTator, text mining | PubMed |
| Obeticholic acid as an index farnesoid X receptor scaffold in metabolic dysfunction-associated steatohepatitis: a testable model for efficacy-liability separation and biomarker interpretation. | Front Pharmacol | 2026 | 42643712 | PubTator, text mining | PubMed |
| Peroxisomal disorder associated with ACOX1 gain-of-function mimicking neuroinflammatory disease. | Neuromuscul Disord | 2026 | 42636650 | PubTator, text mining | PubMed |
| Iridium Nanoparticle-Gated Janus Nanomachines for Enzyme-Controlled Drug Delivery. | ACS Appl Nano Mater | 2026 | 42621422 | PubTator, text mining | PubMed |
| MCPB-21 targets glycogenin-2 to regulate fatty acid oxidation and promote ferroptosis of breast cancer. | Am J Cancer Res | 2026 | 42597491 | PubTator, text mining | PubMed |
1 to 10 of 2,671
See all 2,671 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51
GET https://conductscience.org/api/genes/v1/51/patents?page=2