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Gene · 51

ACOX1: acyl-CoA oxidase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACOX1: acyl-CoA oxidase 1. Genes, record 51. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51

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Gene

Symbol
ACOX1
HGNC
Name
acyl-CoA oxidase 1
HGNC
NCBI Gene ID
51
NCBI Gene
HGNC ID
HGNC:119
HGNC
Ensembl
ENSG00000161533
NCBI Gene
Aliases
ACOX, AOX, MITCH, PALMCOX, SCOX
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15067Peroxisomal acyl-coenzyme A oxidase 16600Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21343Q15067Espacenet
JP 2026004568 A2026-01-1436273Q15067Espacenet
EP 4650780 A22025-11-194088Q15067Espacenet
JP 2025517970 A2025-06-124088Q15067Espacenet
JP 2025062604 A2025-04-141882Q15067Espacenet
JP 2023521663 A2023-05-25342Q15067Espacenet
US 11446398 B22022-09-201882Q15067Espacenet
JP 2022524081 A2022-04-27104853Q15067Espacenet
JP 2021530985 A2021-11-18450Q15067Espacenet
WO 2021202604 A12021-10-07343Q15067Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,171

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACOX1 papersNewest fiscal year
ZIABC005562Xenobiotic receptors102025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers92025
R01NS017950Precursors of Stroke Incidence and Prognosis62025
P30ES010126UNC Center for Environmental Health and Susceptibility52025
P30CA016672Cancer Center Support Grant42025
P30DK063491Diabetes Research Center (DRC)42025
P30CA008748Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025
P30DK020579Diabetes Research Center32025

1 to 10 of 1,171Source NIH's project files

See all 1,171 nih grants

Papers2,671

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrating in vivo metabolism, pharmacokinetics, and dual-indicator scoring for PK-marker selection of Celosiae Semen saponins.J Pharm Biomed Anal202742815117PubTator, text miningPubMed
Multi-omic profiling and pathways related to changes in liver histology after Roux-en-Y gastric bypass: a longitudinal study.EBioMedicine202642810054PubTator, text miningPubMed
ACOX1 downregulation contributes to macrophage M1 polarization and neutrophilic airway inflammation in asthma.Int Immunopharmacol202642772039PubTator, text miningPubMed
FSCN1 Modulates Fatty Acid Metabolism and the Coordinated Activation of AKT/mTOR and p38 MAPK Pathways in Colorectal Cancer Cells.Oncol Res202642769853PubTator, text miningPubMed
Impaired Photorespiratory Metabolism Underlies the Decline in CO2 Assimilation Induced by Alternative Oxidase Inhibition in Rumex K-1 Leaves.Plants (Basel)202642739504PubTator, text miningPubMed
Aryl hydrocarbon receptor as a molecular mediator in the induction of human aldehyde oxidase gene expression.J Pharmacol Exp Ther202642664535PubTator, text miningPubMed
Obeticholic acid as an index farnesoid X receptor scaffold in metabolic dysfunction-associated steatohepatitis: a testable model for efficacy-liability separation and biomarker interpretation.Front Pharmacol202642643712PubTator, text miningPubMed
Peroxisomal disorder associated with ACOX1 gain-of-function mimicking neuroinflammatory disease.Neuromuscul Disord202642636650PubTator, text miningPubMed
Iridium Nanoparticle-Gated Janus Nanomachines for Enzyme-Controlled Drug Delivery.ACS Appl Nano Mater202642621422PubTator, text miningPubMed
MCPB-21 targets glycogenin-2 to regulate fatty acid oxidation and promote ferroptosis of breast cancer.Am J Cancer Res202642597491PubTator, text miningPubMed

1 to 10 of 2,671

See all 2,671 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51

GET https://conductscience.org/api/genes/v1/51/patents?page=2