Gene · 51024
FIS1: fission, mitochondrial 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FIS1: fission, mitochondrial 1. Genes, record 51024. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51024
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y3D6 | Mitochondrial fission 1 protein | 152 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46374 | Q9Y3D6 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 587 | Q9Y3D6 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1576 | Q9Y3D6 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1576 | Q9Y3D6 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 587 | Q9Y3D6 | Espacenet |
| EP 4484957 A1 | 2025-01-01 | 234 | Q9Y3D6 | Espacenet |
| WO 2023162878 A | 2023-08-31 | 234 | Q9Y3D6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32181 | Q9Y3D6 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4160 | Q9Y3D6 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 135152 | Q9Y3D6 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,753
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FIS1 papers | Newest fiscal year |
|---|---|---|---|
| ZIANS002859 | Targeting Protein Aggregates for Autophagosomal Degradation | 14 | 2025 |
| ZIANS003123 | Role of mitochondria in neurodegenerative diseases | 11 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 8 | 2025 |
| ZIANS003127 | Mechanisms of Autophagy | 8 | 2025 |
| R01AA011147 | Ethanol and aldehyde dehydrogenases in health and disease | 7 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 5 | 2025 |
| R01HL091469 | Cysteine oxidation in the heart | 5 | 2025 |
| R01MH128022 | Defining brain pericytes as a novel and myeloid-derived HIV reservoir | 5 | 2025 |
1 to 10 of 1,753Source NIH's project files
See all 1,753 nih grantsPapers3,164
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Polydatin improves mitochondrial dynamics dysrhythmia by regulating BMAL1 to prevent and treat metabolic dysfunction-associated fatty liver disease. | J Ethnopharmacol | 2027 | 42468884 | PubTator, text mining | PubMed |
| Mitochondrial Quality Control: A Gatekeeper of Spermatogenesis. | J Vis Exp | 2026 | 42813713 | PubTator, text mining | PubMed |
| Benzamil-induced cytotoxicity in non-small cell lung cancer is associated with mitochondrial damage, mitochondrial elongation, and altered XIAP signaling. | J Pharmacol Sci | 2026 | 42810781 | PubTator, text mining | PubMed |
| Mitophagy-Related Gene Dysregulation: Links With Telomere Attrition and Impaired Lung Function in Sulfur Mustard-Exposed Veterans. | J Appl Toxicol | 2026 | 42775893 | PubTator, text mining | PubMed |
| Recent advances in mitochondrial fission and fusion in diabetic cardiomyopathy. | Front Cardiovasc Med | 2026 | 42761440 | PubTator, text mining | PubMed |
| ARMC10 (S43) phosphorylation mediates trimethyltin chloride-induced cognitive impairment through mitochondrial dynamics disruption. | J Hazard Mater | 2026 | 42748816 | PubTator, text mining | PubMed |
| Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation. | Cell Rep | 2026 | 42715104 | PubTator, text mining | PubMed |
| Septic Cardiomyopathy and Mitochondrial Quality Control. | Front Biosci (Landmark Ed) | 2026 | 42690004 | PubTator, text mining | PubMed |
| Lactylation in sepsis-associated acute kidney injury: regulatory mechanisms and therapeutic prospects. | Front Mol Biosci | 2026 | 42688716 | PubTator, text mining | PubMed |
| Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma. | Genome Res | 2026 | 42680560 | PubTator, text mining | PubMed |
1 to 10 of 3,164
See all 3,164 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51024
GET https://conductscience.org/api/genes/v1/51024/patents?page=2